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Biomedical subjects

D Rohrmann

Publications and source records attributed to D Rohrmann.

23 records · Page 2Linked to original sources

Biofeedback in the treatment of voiding disorders in childhood.

Voiding disorders are a common problem in pediatric urology. Biofeedback is a non-invasive method in the treatment of voiding disorders in childhood. Biofeedback takes aim at the learning or relearning of influencing involuntary functions. We report about our preliminary results of biofeedback training in the treatment of the enuretic syndrome in children. Out of 26 children with pseudo-detrusor-sphincter-dyssynergy 17 could be completely cured and 5 improved considerably. Out of 21 children with motor urgency 9 could be completely cured and 7 children improved. Biofeedback is a successful method to treat children with the enuretic syndrome.

Biofeedback, Psychology↗

[Pathophysiology of primary renal pelvis outflow stenosis].

Ureteral peristalsis originates in the most proximal parts of the caliceal system. It is then conducted to the ureter by way of myogenic excitation conduction. In the pyeloureteral region, however, there seems to be some sort of physiological blockade and modulation of activity. It depends on the level of diuresis whether only a few or all contractions of the renal pelvis reach the ureter. Morphological and functional investigations show that the pathophysiological disturbance in cases of primary stenosis of the pyeloureteral junction seems to be a complete blockade of myogenic excitation conduction. The principle of open surgical corrections (dismembered pyeloureteroplasty) is not only to create a widely open connection between renal pelvis and ureter but also to remove the misfunctioning pyeloureteral segment and to substitute it by a region of improved myogenic excitation conduction.

Animals↗

[Preoperative staging and follow-up in rectal cancer using endorectal sonography].

32 patients suffering from rectal carcinoma were examined by endorectal sonography. The preoperative staging by sonography was compared with digital palpation, colon enema and computertomography of the pelvis. In 90% of the cases the sonographic determination of the grade of invasion was identical to the histopathological examination. The efficiency of local destruction methods of rectal carcinoma (cryotherapy) can be controlled by this method.

Biopsy↗

[Pharmacologic modification of ureteral activity].

The renal pelvis and the ureter represent a functional system with myogenic excitation generation and conduction. The activity of this system is modulated by the autonomic nervous system: alpha-adrenergic and cholinergic substances stimulate, beta-adrenergic drugs inhibit the pyeloureteral activity. Besides the sympathetic nervous system with adrenergic postganglionic excitation conduction and the parasympathetic nervous system with cholinergic transmission, non-adrenergic, non-cholinergic systems appear to exist. Vasoactive intestinal peptide (VIP), e.g., markably decreases the frequency and amplitude of the ureteral activity. Calcium antagonists (e.g. nifedipin) lead to a direct inhibition of the ureteral activity: the quick phasic contractions are selectively oppressed without any influence on the tonic activity of the pyeloureter. A direct therapeutic modulation of the ureteral activity, however, e.g. to treat a colic or to accelerate the spontaneous discharge of stones, seems to be only rarely possible: Glucagone shows a markable decrease of ureteral peristalsis in animal experiments. Antagonists of prostaglandine proved to have not only an antiinflammatory and central analgetic effect but they also influence the pyeloureter directly by relaxing the muscular layer.

Acetylcholine↗