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Biomedical subjects

D Robertson

Publications and source records attributed to D Robertson.

545 records · Page 31Linked to original sources

Baby bottle tooth decay in Native American children in Head Start centers.

Baby bottle tooth decay is a unique pattern of dental caries (tooth decay) affecting the dentition of young children. It is associated with the practice of putting the child to sleep with a nursing bottle filled with liquid that contains sugar. Practitioners who treat Native American children have noted that this population suffers from a high prevalence of the condition. In order to establish specific program priorities and treatment needs for this segment of the Native American population, additional information is required on both prevalence and severity of baby bottle tooth decay. In this survey, an overall prevalence of 70 percent was observed when Navajo and Cherokee Head Start students ages 4-5 years were examined. Of the children affected by baby bottle tooth decay, 87 percent displayed the most severe manifestation of the disease. The prevalence of this disease in these Native American children appears to be substantially higher than in other populations. Further study is needed to identify the factors contributing to this difference in prevalence and to identify effective measures for reducing the occurrence of baby bottle tooth decay among Native Americans.

Arizona↗

Localization of dopamine-beta-hydroxylase-like immunoreactivity in the superior olivary complex of the rat.

The noradrenergic (NA) innervation of the superior olivary complex (SOC) was investigated using a monoclonal antibody against dopamine-beta-hydroxylase (D beta H), the synthesizing enzyme for noradrenaline. In addition, positive labelling of D beta H in the inferior colliculus, the lateral lemniscus (LL) and the cochlear nucleus were documented. The antibody was detected using the highly specific and sensitive ABC immunocytochemical method. The specific aim of the study was to show the distribution of putative NA cells and fibres in the SOC in greater detail than had been previously reported. All investigated auditory regions contained D beta H-positive fibres in varying densities. All superior olivary and periolivary nuclei showed NA innervation by mainly fine, weakly staining fibres. Both nuclei of the LL were also found to contain D beta H-positive fibres. D beta H-positive cell bodies were found in the region of the ventral lateral lemniscus and immediately lateral and dorsal to the lateral superior olivary nucleus. Thus the NA innervation of the superior olivary complex could originate from these regions and/or the locus coeruleus.

Animals↗