Biomedical subjects
Publications and source records attributed to D Remzi.
This review of 69 infants (up to two years old) with full preoperative workup, all with urinary calculus disease, covers a fifteen-year period and shows a high incidence of this disease in Turkey when compared with other studies in the literature. It also presents cases of urolithiasis in infancy which, to date, have not been treated as a separate phenomenon.
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A case of retroperitoneal fibrosarcoma is reported. Clinical and pathological signs of the lesion and its treatment are emphasized.
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A complete evaluation of 1337 cases from a total of 1799 children seen with urinary tract stones was made. Factors known to be associated with this disease have been carefully documented. No definite conclusions as to the etiology of the disease could be drawn. However, malnutrition, lower socio-economic homes, sex (male:female = 5:1) and occurrence from a younger age were the most consistent predominant factors.
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The effect of calcium antagonists nifedipine and verapamil on spontaneous rhythmic contractions of human isolated ureter obtained from donor subjects undergoing kidney transplantation was investigated in comparison with a nonsteroidal antiinflammatory drug indomethacin. Stop-times i.e. the time elapsing from application, were determined for each drug. The rank order of potency at 10(-8) and 10(-7) M concentrations of the drugs was: nifedipine > verapamil > or = indomethacin. However, no significant difference of the stop-times was observed at 10(-6) M concentration of the drugs tested. The rhythmic contractions were re-activated by PGF2 alpha after stoppage with indomethacin but not with nifedipine or verapamil. These results suggest that not only endogenous PG synthesis but also an influx of calcium from the extracellular space is responsible for the spontaneous rhythmic activity of human ureter. The beneficial effects of using calcium antagonists in the treatment of ureteric colic is discussed.