Search PubMed⌕ Search

Biomedical subjects

D R Sanders

Publications and source records attributed to D R Sanders.

113 records · Page 7Linked to original sources
PubMedDate not supplied

Posterior chamber phakic intraocular lens for hyperopia.

PURPOSE: A Phase I U.S. FDA clinical study of a plate haptic posterior chamber phakic intraocular lens (STAAR Surgical Implantable Contact Lens) for treatment of hyperopia was conducted at 4 sites in the United States. The purpose of this report is to assess the short-term safety and efficacy. METHODS: Ten patients with hyperopia between +2.50 and +10.875 D were implanted in one eye each with the posterior chamber plate phakic intraocular lens and were examined at baseline and 1 day, 1 week, 1, 3, and 6 months after surgery. Mean baseline hyperopia was +6.63 D. RESULTS: At 6 months postoperatively, 7 of 10 eyes (70%) had an uncorrected visual acuity of 20/20 or better and 10 of 10 (100%) had 20/40 or better. Eight of ten eyes (80%) had a spectacle-corrected visual acuity within 1 line of baseline; the other two eyes (20%) had an improvement of 3 lines. Mean 6-month postoperative spherical equivalent refraction was +0.20 +/- 0.61D (range, -0.50 to +1.50 D), a reduction of 6.025 D from baseline. Eight of 10 eyes (80%) were within +/-0.50 D of emmetropia, 9 eyes (90%) were within +/-1.00 D, and all eyes (100%) were within +/-1.50 D. No operative or postoperative complications or adverse reactions were observed. CONCLUSIONS: Results support the short-term safety, efficacy, and predictability of the STAAR Surgical Implantable Contact Lens (plate haptic posterior chamber phakic intraocular lens) in the treatment of hyperopia.

Adult↗
PubMedDate not supplied

Radial thermokeratoplasty for the correction of hyperopia.

Hyperopic thermokeratoplasty involves making controlled thermal burns in the corneal stroma in a radial pattern up to a premarked clear zone. It steepens the central cornea and reduces the hyperopia. A series of 117 radial thermokeratoplasty eyes done in the Soviet Union were analyzed. Mean preoperative hyperopia of +5.27 diopters (range = +0.50 to +17.00 D) was reduced at 12 months after surgery by a mean of -3.48 D, resulting in a mean postoperative spherical equivalent of +1.84 D. Average correction was 70.8%. Forty percent of eyes were corrected to less than 1.00 D residual refractive error; however, 58% were undercorrected by 1.00 D or more. The proportion of eyes seeing 20/40 or better unaided increased from 10% preoperatively to 52% by 3 months after surgery and remained at 53% at 12 months after surgery. Overall refractive stability was demonstrated during the 1st postoperative year. Stepwise regression showed that none of the preoperative or surgical factors significantly predicted outcome when all eyes were evaluated.

Adolescent↗
PubMedDate not supplied

Delayed regression of effect in myopic epikeratophakia vs myopic keratomileusis for high myopia.

We compared the effectiveness and stability of our first six consecutive myopic epikeratophakia procedures (mean follow-up 18 months, range 14 to 26) with our first four consecutive cryolathe myopic keratomileusis procedures (mean follow-up 28 months, range 14 to 35). Myopic keratomileusis reduced preoperative myopia (range -8.9 to -12.1 diopters) by 77% to 94% in four patients. Refraction and visual acuity remained stable for over 1 to 3 years. In contrast, only three of the six myopic epikeratophakia procedures had stable results. The remaining three eyes which were within 0.38 D of emmetropia at the time of suture removal showed a loss of effect, resulting in myopia worse than their preoperative values in two eyes and a small correction in one eye. Only one of the six eyes achieved an uncorrected visual acuity better than 20/200. We conclude that myopic keratomileusis may be the procedure of choice for treating individuals with myopia of -8 to -15 D, because the incidence of late regression of effect after myopic epikeratophakia using the techniques in this study is unacceptable.

Adult↗