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Biomedical subjects

D R Idler

Publications and source records attributed to D R Idler.

At least 37 records · Page 2Linked to original sources
PubMed1985

Plasma vitellogenin in landlocked Atlantic salmon (Salmo salar Ouananiche): isolation, homologous radioimmunoassay and immunological cross-reactivity with vitellogenin from other teleosts.

Vitellogenin was isolated by affinity chromatography and gel filtration from landlocked Atlantic salmon plasma. Vitellogenin was labelled with iodine-131 using iodogen and an homologous radioimmunoassay was developed. There was poor immunological cross-reactivity with vitellogenin or plasma from other teleosts. Parallelism of the vitellogenin standard to the displacement by plasma of vitellogenic salmon allowed the assay to be used to evaluate the seasonal concentration profile of vitellogenin in female adult salmon. Extracts of liver or ovary from female Atlantic salmon also yielded displacements parallel to the vitellogenin standard in the assay.

Animals↗
PubMed1984

Failure of antibody to carbohydrate-rich gonadotropin to inhibit rapid ovarian growth in landlocked Atlantic salmon.

The discovery of a carbohydrate-poor gonadotropin has resulted in a reassessment of the role of the classical, carbohydrate-rich gonadotropin (Con A II GtH) in teleost ovarian development. Prolonged treatment of landlocked Atlantic salmon with antibody to Con A II GtH failed to inhibit rapid ovarian growth or accumulation of triglyceride or vitellogenin derivative. Sera from antibody-treated fish showed substantial capacity to bind Con A II GtH indicating that antibody treatment successfully removed endogenous Con A II GtH from the circulation. These results are consistent with previous reports that a factor other than Con A II GtH is responsible for stimulating yolk accumulation.

Animals↗
PubMed1983

Impairment of early ovarian growth in landlocked Atlantic salmon by an antibody to carbohydrate-rich gonadotropin.

The role of the carbohydrate-rich gonadotropin (Con AII GtH) in an early phase of ovarian growth in landlocked Atlantic salmon (Salmo salar) was investigated by treating in vivo with an antibody to chum salmon (Oncorhynchus keta) Con AII GtH (anti-Con AII). Anti-Con AII treatment significantly inhibited ovarian growth but did not consistently lower serum levels of vitellogenin. This suggests that Con AII GtH is necessary for early ovarian growth and, has one or more functions in early ovarian growth in addition to stimulation, via estrogen, of vitellogenin production.

Animals↗
PubMed1983

Effect of acute exposure to crude petroleum on some reproductive hormones in salmon and flounder.

1. The concentration of total (free + conjugated) androgens in plasma of sexually mature male salmon and flounder was generally lower in oil-exposed fish. 2. Exposure to crude oil inhibited some testicular development of salmon during the final stages of maturation. 3. Oil exposure had no effect on levels of total plasmatic androgens or estradiol in male and female flounder during gonadal recrudescence. 4. Aryl hydrocarbon hydroxylase activity increased in liver and kidney of both species. 5. Sperm, collected from salmon exposed to oil, fertilized eggs from non-exposed females to produce normal alevins.

Androgens↗