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Biomedical subjects

D R Donaldson

Publications and source records attributed to D R Donaldson.

41 records · Page 3Linked to original sources

Vertical abdominal incisions--a choice?

A prospective randomized trial was carried out on 207 patients undergoing laparotomy using three different vertical abdominal incisions--midline, 'medial' paramedian incision and 'lateral' paramedian incision. The lateral paramedian incision is slightly more time-consuming to perform than the other two incisions but there is a statistically greater incidence of incisional hernia in midline and medial paramedian wounds than with the lateral paramedian incision. It is suggested that when a vertical abdominal incision is being considered the lateral paramedian should be the incision of choice.

Adolescent↗

The value of laparoscopy under local anaesthesia in 250 medical and surgical patients.

This study reports our experience of laparoscopy under local anaesthesia in 250 patients; the procedure was safe, quick and easy to perform with minimal inconvenience to the patient. We advocate the early use of laparoscopy in patients with ascites and when there is difficulty in the diagnosis of patients with jaundice and hepatomegaly, an accurate histological diagnosis being obtained in the majority. In patients with intra-abdominal malignancy, in whom surgery is planned, laparoscopy can detect disseminated disease and so avoid an unnecessary laparotomy. Laparoscopy may also provide a diagnosis in patients presenting with a variety of vague symptoms such as abdominal pain, weight loss, lethargy etc. We have found laparoscopy an excellent investigation if positive but, as if only allows the surface inspection of viscera, when negative, we recommend caution in its interpretation.

Abdominal Neoplasms↗

High density lipoproteins and exercise.

High density lipoprotein (HDL) and total cholesterol (TC) levels have been measured and their ratio compared in four groups of subjects - those with vascular disease, controls, middle-aged "keep-fit" enthusiasts and young physical education students. Each group has also been subjected to analysis of risk factors known for atherosclerosis. The HDL level was significantly raised in the Athletic and Exercise groups even though the latter were more overweight and had the highest total cholesterol level. This would appear to indicate that exercise may exert its protective effect against atherosclerosis, at least in part, by elevating the HDL level above a certain critical level. The HDL/TC ratio was significantly lower in the Vascular group and we would advocate that any ratio less than 20% is highly suspicious of atherosclerosis. We suggest that both the HDL level and HDL/TC ratio should be viewed together as reflecting the risk of atherosclerosis.

Blood Pressure↗