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Biomedical subjects

D R Barry

Publications and source records attributed to D R Barry.

At least 19 recordsLinked to original sources

Changes in medical education: the community perspective.

The societal and economic forces driving change in medical education are affecting communities as well as universities. Each of the four authors of this paper is deeply involved in one of the components of their locale's well-developed community-based medical educational system, and each describes how change is influencing his role in that system, whether the role be managing a community hospital, directing a local Area Health Education Center, participating as a family medicine faculty member, or being a community preceptor. They agree on some common themes: (1) that it is good that medical students' education is moving into the community (e.g., this validates the importance of the community hospital to medical education, is an acknowledgment of the importance of generalism, and provides students invaluable learning experiences); (2) that educating medical students in the community is expensive, and more funding and resources are needed so that the area's hospitals, community faculty, preceptors, and support services can be fairly compensated for their commitment; and (3) that their community-based education system can no longer absorb the costs of training more medical students. This is not a criticism of academic medical centers, which are under tremendous financial pressures themselves, but is simply to state the community perspective and to urge fairness in the distribution of resources for medical education. Community institutions and academic medical centers will work individually to create their own integrated health care systems but must work together to create a better, more cost-effective system for educating medical students.

Academic Medical Centers↗

Aplasia of the optic nerves.

At birth, a full term baby showed marked cyanosis and respiratory distress, resulting from transposition of the great vessels. In spite of intensive care, and of balloon septostomies, the child died at the age of five days. The right eye was small and had an almost fully opaque cornea, together with other abnormalities of the anterior segment; the left eye was slightly larger, with a clear cornea. Both eyes showed varying degress of retinal dysplasia, and foci of microcystoid change. Macroscopically, and on histological examination of serial sections, the central retinal vessels were completely absent (a focus of neovascularisation in the vitreous of the right eye was apparently of choroidal origin). Furthermore, no optic discs, retinal ganglion cells and nerve fibres could be demonstrated. The optic nerves were missing. The findings are discussed.

Adult↗

Histopathological changes after pseudophakos.

Cataract extraction and iris clip lens implantation in an 88-year-old woman were followed by hyphaema, anterior uveitis and organised exudates around the implant. The globe was enucleated after 15 months due to pain and a poor visual prognosis. Sections showed an epithelial downgrowth into part of the anterior chamber, associated with a fibrous membrane which had surrounded part of one loop of the implant. Atrophy of the iris, adenomatous changes in a ciliary process and an after-cataractous ring were noted. Inflammatory changes were present in the uvea, associated posteriorly with degenerative choroido-retinitis, probably of arteriosclerotic origin. The nylon loops of the implant showed areas of biodegradation and were partly fibrosed in. The possible relationship of the various changes is discussed.

Aged↗

A case of the cryptophthalmos syndrome.

A case of the cryptophthalmos syndrome is presented, showing bilateral absence of separate eyelids and of the palpebral fissure, the facial skin being continuous over both eyes. Low set ears, marked syndactylies, absence of the urinary tract and external genital hypertrophy were noted, while laryngeal atresia allowed a survival of 5 min only at birth. Histopathological study showed the absence of the conjunctiva, and the ectopic lens surrounded by coarse connective tissue in both eyes. The eyes showed a single chamber: no normal corneal elements, iris or anterior chamber were identifiable and the ciliary body was abnormal. An excessive vascularisation of the peripheral retina and a subretinal deposit of lenticular bladder cells were additional features. The karyotype was that of a normal female.

Abnormalities, Multiple↗

HLA antigens and certain types of uveitis.

Some preliminary results are given on human leucocyte antigen (HLA) typing of nine patients with sympathetic ophthalmitis, two with Vogt-Koyanagi-Harada disease, and nine with Behçet's disease and uveitis. In the sympathetic ophthalmitis patients the relative risk for B40 was 7.2, which would indicate that a more extensive study might be valuable. In Behçet's disease B5 and B27 both carried increased risks of 9.4 and 11.1 respectively.

Behcet Syndrome↗