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Biomedical subjects

D Pokorni

Publications and source records attributed to D Pokorni.

7 recordsLinked to original sources

[Meningococcal carrier state and meningococcal diseases in a military unit].

In four recently formed military units pharyngeal meningococcal carrier state and dynamics of nasopharyngeal meningococcal infections have been examined. Carrier state found in at least 50% of recruits at their entering the army has been increased during the first two months for 10-26.4% and it was associated with very significant dynamics of meningococcal infection: changes in carrier state during the first two months have been found in 61.3% of soldiers with very marked changes in distribution of some meningococcal serologic groups among isolated species. Two months later stagnation and lower percentage of the carrier state was observed together with reducing dynamics of meningococcal infection. Meningococcal disease did not occur in the examined environment and this was explained by the absence of virulent meningococcal serotypes. It was concluded that in the risk for meningococcal disease evaluation final identification of meningococcal species isolated from patients and their contacts should be made aiming to timely detection of species known to have significant degree of virulence.

Bacterial Infections

[Lyme disease in Yugoslavia].

Presented are results of the last five-year period study of the lyme disease in Yugoslavia. On the basis of published papers and professional communications over 2500 cases of lyme disease.were detected in our country within this period. Presented are common epidemiologic and clinical features of the disease and particularly cases diagnosed in Belgrade. Since 1987 a group of various specialists has been working on the research project in collaboration with many centres in the country. Indirect immunofluorescence test as the diagnostic laboratory technique has been introduced in the Military Medical Academy in Belgrade in 1987. First species of Borrelia burgdorferi from ticks Ixodes ricinus have been isolated and cultivated in May and June 1990. Current problems concerning research work, medical and epidemiological aspects of the lyme disease are presented.

Adolescent

[Use of the ELISA immunoenzyme test and indirect immunofluorescence in the diagnosis of a toxoplasmosis epidemic].

Etiologic agent of lymphadenitis outbreak in one our military environment was detected by two serologic tests: ELISA (enzyme-linked immunosorbent assay) and indirect immunofluorescence test (IIF) both specific for IgM and IgG antibody detection in toxoplasmosis diagnosis. IgM-ELISA analysis of the first serum sample taken from a group of 79 soldiers with lymphadenitis was positive in 65 examinees (82.28%) and IgG-IIF technique in 52 (65.82%). In a group of 33 soldiers from the same unit with no signs of the disease IgM-ELISA test was positive in 12 (36.36%) and IgM-IIF in 9 (27.27%). In a group of 40 officers from the unit with the disease outbreak specific IgM antibodies were found by both tests only in the head cook. IgM antibodies were not found in a control group of 102 healthy soldiers from other units of the same garrison. Results of this investigation thermal injury showed variations in immune response to infection in dependence on trauma effect duration (in dependence on the phase). In the early posttraumatic phase organism is capable to react effectively to the inoculated infective agent and in the late posttraumatic phase this reaction is much less effective. Authors conclude that these results may influence upon the thermal injury management strategy in dependence on the trauma effect duration.

Disease Outbreaks