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Biomedical subjects

D Piatowska

Publications and source records attributed to D Piatowska.

At least 19 recordsLinked to original sources

[Histopathological and immunohistochemical investigations of chronic periapical inflammations of permanent teeth].

Histopathological investigations were done in 72 cases of periapical granulomas and 9 cases of periapical cysts demonstrating that both granulomas and cysts were composed of granulation tissue varying in maturity. Immunohistochemical studies by the peroxidase method PAP showed the presence of light chains (kappa and lambda) and heavy chains (IgA, IgM, IgG, IgE). In the chronic inflammatory infiltrates of granulomas and cysts plasma cells with IgG prevailed. These observations suggest that specific immune reactions participate in the pathological mechanism of chronic periapical inflammatory processes.

Adolescent↗

[Histopathologic and histobacteriologic studies of chronic periapical changes of the permanent teeth].

Chronic periapical lesions were recognized clinically and radiologically in 109 patients aged from 10 to 79, twice as frequent in the maxilla as in the mandible. Histopathological analysis revealed periapical granulomas and cysts. Forty-eight periapical granulomas were studied histobacteriologically. Detailed microscopic analysis of these cases in order to find bacteria was negative. Histopathological analysis of 72 periapical granulomas and 13 cysts (including four follicular cysts) revealed mixed forms apart from homogenous granulomas. In addition changes in the composition of infiltrate cells are rather qualitative than quantitative, therefore classification of periapical lesions into periapical granulomas and cysts seems justified and sufficient for diagnostic and clinical needs. Detailed analysis of cellular composition of periapical granulomas and cysts shows that immunologic agents may play a role in the pathomechanism of these lesions.

Adult↗

Electron microscopic study of peripheral giant-cell reparative granuloma.

Six giant-cell tumors have been examined by electron microscopic methods in order to determine their histogenesis and to expand knowledge of cell structures. The examination of giant cells revealed an abundance of cell organelles, especially mitochondria. Apart from typical stromal cells, such as fibroblasts, macrophages, and mast cells, clusters of stromal "light" cells were often found with an intimate relation between their cell membranes. The role and function of these cells is not well known. Between fibroblasts of regular appearance with a small number of cytoplasmic organelles, others were found with an incrased number of mitochondria. These cells often formed aggregates. This suggests that giant cells develop through the association of stroma fibroblast cells.

Cell Nucleus↗