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Biomedical subjects

D Petersen

Publications and source records attributed to D Petersen.

At least 127 records · Page 7Linked to original sources

[Neuroradiology, clinical picture and pathology of cerebral venous angiomas].

Twelve cases of venous angioma of the brain are presented. The neuroradiological and clinical findings in our series as well as in 45 previously reported cases are summarized. Angiography shows a normal arterial phase but consecutively a network or medusa-like pattern of numerous dilated medullary veins. converging towards one or several draining vessels with transcerebral course. The angiographic appearance is characteristic but not uniform, showing subgroups with faint blush, early filling veins and drainage into different directions. Some cases of venous malformations cannot be classified on the basis of angiographic findings and differentiation of telangiectases or cavernomas may be difficult. CT findings are non-specific, but contrast-enhanced CT almost invariably shows an enlarged transcerebral vessel, suggesting the presence of venous malformation. The lesion has to be classified as a vascular hamartoma. Although not an uncommon finding at autopsy venous angioma has been considered rare, because its clinical and radiological characteristics are little known. Though it may be asymptomatic, more than 30% of the reported cases (50% in our series) suffered from epileptic seizures. In about 10% of all cases symptoms of intracranial hemorrhage related to venous angioma were observed.

Adolescent↗

Pulmonary function in Klinefelter's syndrome.

We evaluated pulmonary function in 24 patients with Klinefelter's syndrome. Of these, two had an obstructive defect, nine had a restrictive defect, and 11 had a decreased functional residual capacity. Since none had evidence of lung parenchymal disease, the restrictive syndrome may be due to chest wall abnormality.

Adolescent↗

[The radiological demonstration of vessels in embryos and foetuses. Comparative radiological studies of the venous system of the neck, head and brain in domestic animals. Paper 3 (author's transl)].

A method was developed for prenatal, post-mortem angiography, post-mortem angiography of the venous system of the brain, head and neck; its development was studied in the embryos and foetuses of 80 cattle, 20 sheep and 20 pigs with a crown-rump lenght of 19 to 155 mm. Radiological and corrosion preparations were studied. The embryonic and foetal venous systems were filled with thin barium sulphate through the umbilical and omphalic veins. The development and transformation of the cerebral veins and sinuses are compared and are related to the corresponding vascular anatomy of the adult animal and to man. The radio-embryological method for demonstrating cerebral vessels is also applicable to live foetuses.

Animals↗

Treatment effectiveness as judged by successfully and unsuccessfully treated alcoholics.

Thirty-seven successfully and 46 unsuccessfully treated male alcoholics were asked to judge the effectiveness or ineffectiveness of six treatment methods routinely offered by a state hospital. For each treatment method, the total frequencies of judgments of most and least helpful, respectively, were as follows: detoxification (16%, 14%), lectures (16%, 20%), group therapy (54%, 7%), individual counseling (26%, 6%), work therapy (17%, 22%) and family therapy (13%, 14%). The two groups of subjects differed significantly in the frequencies of treatment methods judged to be "least helpful", but not in the frequencies of "most helpful" treatment. The similarity between the judgments of successfully and unsuccessfully treated alcoholics might reflect the positive effects of previous treatment in the unsuccessful group.

Adult↗

Rotational cerebral roentgenography. I. Evaluation of the technical procedure and diagnostic application with model studies.

A rotational cerebral roentgenographic technique with a 70 mm camera is elaborated in model studies of the plain and cerebrovascular system. The tube-camera-unit rotates in a semicircle in 5 to 6 seconds around a skull placed in the isocentrum. All special projections of the skull are obtained routinely during one rotational manoeuvre, and intracranial calcifications, foreign bodies and abnormalities of the calvarium are demonstrated sequentially in oblique or tangential views. Studies of the basal cerebral arteries have shown that the localization, size and configuration of arterial aneurysms and stenoses can be demonstrated reliably without changing the position of the skull. An exposure frequency of 6/sec results invariably in excellent stereoscopic views. The diagnostic value and applicability of this technique is discussed.

Cerebral Angiography↗