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Biomedical subjects

D Pelet

Publications and source records attributed to D Pelet.

15 recordsLinked to original sources

Clinical outcome and follow-up of prenatal hydronephrosis.

Between 1987 and 1991, 160 hydronephrotic kidneys were diagnosed prenatally and confirmed postnatally in 100 infants. The aim of the study was to describe the natural history and management of primary hydronephrosis detected prenatally. We devised a new classification of obstructive uropathy outcome using ultrasonography and the diethylenetriamine penta-acetic acid scan. Accordingly, we classified the patients as having mild, moderate or severe hydronephrosis. Nine patients had pyeloplasties and 5 had ureteric reimplantations. We conclude that in most cases there is no need for immediate surgery, and that the initial approach to the management of congenital hydronephrosis should be conservative. We suggest that anti-bacterial prophylaxis be conventionally given to infants with vesicoureteral reflux and for the first 6 months of life to infants demonstrating moderate to severe newborn primary hydronephrosis.

Female↗

Evaluation of prenatally diagnosed hydronephrosis by morphometric measurements of the kidney.

A large number of hydronephrotic kidneys (108) were diagnosed prenatally in 69 infants between 1987 and 1991 and subsequently confirmed postnatally. Prenatal morphometric measurements were done in order to find reliable parameters for the detection of a group at risk for surgical treatment. A second aim of the study was to describe the natural history and management of hydronephrosis detected prenatally. We devised a classification of postnatal obstructive uropathy using ultrasonography and the renal scan. Accordingly, we classified the patients as having mild, moderate or severe hydronephrosis. A renal pelvic antero-posterior diameter (APD) of 9 mm or more, and a pelvic-to-renal APD ratio of 0.45 before 32 weeks of gestation and 0.52 thereafter, were found to be useful for the detection of severe outcome. Our new parameter, a pelvic-to-renal volume ratio of greater than 0.08, can also be used for this purpose.

Algorithms↗

Malignant external otitis: The diagnostic value of bone scintigraphy.

Technetium99m Methylene Diphosphate bone scintigraphy (BS) of the skull was performed in three patients with malignant external otitis (MEO). Pathological uptake of the radioisotope in the mastoid region was found during the early stages of MEO updating radiologic findings. The extent of the radioisotope accumulation during the early stages of MEO indicates that the actual tissue damage exceeds the clinical estimation. The follow-up BS findings correlate well with the clinical course of MEO indicating either healing or extension to the base of skull.

Aged↗

Osteotomy and fixation for hallux valgus.

Osteotomy is a good method for correcting a metatarsus varus and a hallux valgus if the first metatarsophalangeal joint has little or no arthritis, no luxation and is mobile. Osteotomy of the neck of the first metatarsal is recommended when the articular surface of the first metatarsophalangeal joint has a certain lateral obliquity. In these cases osteotomy of the base of the metatarsal, which exaggerates this obliquity, should be avoided. Osteotomy allows correction in all planes. As osteotomy of the diaphysis of the proximal phalanx is indicated in cases where the hallux is too long, is pronated, or if there is a phalanx valga. Internal fixation of these osteotomies with a lag screw has the advantage of maintaining the correction and allowing early mobilization. With the above-described technique, a physiologic as well as an aesthetic reconstruction may be obtained. The osteotomy must be performed very carefully in order to avoid the complications of recurrence of deformity, joint stiffness and pain.

Hallux↗

Thyroid function in hemodialysis.

The relevance of the biochemical evidence of hypothyroidism in patients on regular hemodialysis is debatable. Several indexes of thyroid function were assessed in 46 patients undergoing chronic hemodialysis for 2 to 45 months. Low serum levels of thyroxine were found in 69.5% of the patients studied and of triiodothyronine (T3) in 46.5%. Low values of T3-Sephadex binding were noted in 17.3%, of free thyroxine index (FTI) in 26.3% and of radioiodine uptake in 19.3% of the patients; 13.0% had high levels of thyroid-stimulating hormone (TSH). The overall incidence of hypothyroidism, based on FTI and TSH, was 34.8%. We concluded that the diagnosis of hypothyroidism should be based on FTI and TSH levels, and that chronically hemodialyzed patients tend to exhibit biochemical rather than clinical hypothyroidism.

Adolescent↗

Bone scintigraphic diagnosis in acute frontal sinusitis.

The diagnostic value of Technetium 99m Methylene Diphosphate bone scintigraphy was evaluated in 21 patients, 10 of them with acute frontal sinusitis and a "fluid level" on sinus radiography. Pathologic accumulation of the radioisotope over the region corresponding to the diseased frontal sinus was observed in 9 of these 10 patients, 5 of them having a marked accumulation. The patients with marked accumulation of the bone-seeking radioisotope had a more severe clinical course of the disease than those who had a moderate or no accumulation of the radioisotope. Marked accumulation of the radioisotope was also found in a patient with "inflammatory pseudotumor of the orbit". The radioisotope did not accumulate over the frontal sinus of patients with mucosal swelling or cellulitis of face, or in control patients with mastoid disease. Based on our findings, we recommend bone scintigraphy be performed routinely for diagnosis of acute frontal sinusitis. A marked accumulation of Tc99m MDP indicates inflammatory metabolic changes of the sinus bony walls, predicting a severe clinical course and the necessity of aggressive treatment.

Adult↗