[Neuro-chorio-retinal manifestations in Onchocerca volvulus and Loa loa filariasis associated with malaria].
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Biomedical subjects
Publications and source records attributed to D Panaitescu.
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We record the occurrence of four cases of subconjunctival eye infection due to Setaria labiatopapillosa. The patients are all women, between 35 and 68 years old, all inhabitants of the same neighbourhood of the lake Pantelimon, a well known area for its blood feeding vector insect population and all complained about the same eye affliction: photophobia, eye swelling, tearing and foreign body sensation accompanied by some rash and low eosinofilia (6-8%). The treatment was surgical (excision) and DEC 1 mg/kg body weight. The vector insect cannot be specified. We stress that to our knowledge these are the first reported cases of human infection with Setaria labiatopapillosa.
In order to reveal by absorption spectrophotometry the redox differences between the Plasmodium berghei infected erythrocyte lysates (MEL) and the healthy ones (HEL) we studied their interaction with the neutral red (NR) redox dye. The variation of the dye absorption intensity at 540 nm as a function of the hemoglobin content of the samples was attributed to the redox potential variation of the different hemoglobin aggregates formed in the samples containing different hemoglobin quantities. By short term treatment of the lysates with ascorbic acid in the presence of NR, great redox reactivity difference was proved between MEL and HEL as revealed by absorption and explained by the initial higher oxidation state of the Hb iron in MEL than in HEL.
The present paper reports on the first autochtonous case of amoebic hepatic abscess in Romania in a patient in which the epidemiologic survey showed that there had been no possible import infection. The amoebic abscess was located in the superoexternal area of the right hepatic lobe. Subsequently a major complication developed: a tendency to pleuropulmonary invasion with the formation of fluid in the right pleural cavity. The diagnosis, suggested by the aspect of the abscess cavity, was established by the presence of the parasite in the flaky pleural exudate obtained by puncture, by cultures in Loeffler medium and by serum immunofluorescence. The abscess was evacuated surgically and a specific treatment with Chloroquine and Metronidazol combined with antibiotics and a symptomatic medication was prescribed. The patient recovered and was discharged 51 days after surgery.
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The experimental fusion of Entamoeba histolytica cells after their treatment with horseradish peroxidase is reported. This finding is discussed in relation with the general knowledge about the cell fusion process.
Changes of oxidative processes induced in mouse erythrocytes by Plasmodium berghei were studied in the presence of methylene blue, neutral red or of both cationic redox dyes. The results are discussed in terms of redox and metachromatic modifications of the dyes which are produced by malarial and normal erythrocyte lysates.