A child presenting with hydrocephalus with extensive inactive retinochoroiditis and his mother with a healed toxoplasmic scar is being discussed. Maternal ocular examination in each case of hydrocephalus is recommended, as uveitis work up of the child is often unrewarding.

Chorioretinitis↗

PubMedDate not supplied

Scleral rigidity in glaucoma, before and during topical antiglaucoma drug therapy.

A study of 30 subjects (10 normal and 20 having glaucoma) was done to find out the scleral rigidity in glaucoma cases as compared to normal. The effect of miotics, timolol (0.25%) and pilocarpine (2%) eye drops on the scleral rigidity in cases of glaucoma was observed.

Administration, Topical↗

PubMedDate not supplied

The hypotensive effect of verapamil eye drops on ocular hypertension.

Verapamil eye drops (0.125%) were prepared in phosphate buffer (pH7). Ten patients with unilateral (5 cases) or bilateral (5 cases) ocular hypertension received the drug topically three times daily for two weeks. A significant reduction in the mean ocular tension was observed in 6 right eyes at the end of the first (4.5 mm Hg Schiotz) and second week (7 mm Hg Schiotz) and in 9 left eyes at the end of the second week (6.7 mm Hg Schiotz). The reduction in tension was minimal (1 mm Hg Schiotz) in the eyes with normal initial values. The systolic and diastolic blood pressured dropped by 12.8 mm Hg and 4.0 mm Hg in the first week and by 11.2 mm Hg and 5.4 mm Hg in the second week respectively. There was also a reduction in the mean pulse rate by 7 beats and 13 beats in the first and second week of therapy. These observations indicate persistent hypotensive effect of topical Verapamil on ocular hypertension and some amount of systemic absorption of the drug from eye.

Administration, Topical↗

PubMedDate not supplied

Protein bound iodine levels during oestrus, pregnancy and non-pregnancy states in goats.

Thyroidal function in goats as estimated by PBI values of blood serum showed a very high activity in oestrus, followed by that in pregnancy state. There was significant increase in PBI values between oestrus and non-pregnancy groups. The lack of significance between pregnancy and non-pregnancy values has been explained. Mean PBI values in oestrus, pregnancy and non-pregnancy were respectively 5.91, 5.31 and 3.74 mug/100 ml blood serum.

Animals↗