Re: Acute lobular nephronia.
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Biomedical subjects
Publications and source records attributed to D P Sarma.
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A case is reported of prolonged survival after lobectomy for large cell undifferentiated carcinoma of the lung and resection of metastatic carcinoma of the brain. The patient had survived 11 years 5 months after lung resection and 10 years 4 months after excision of brain metastasis. A review of the reports of another 12 patients who survived 5 years or longer after craniotomy, shows that the surgical excision of a single metastatic lesion of the brain with or without postoperative irradiation offers the best hope for prolonged survival.
A 48-year-old man with a clinical diagnosis of acute appendicitis on exploration was found to have a seminoma in an undescended pelvic testis. The tumor had directly invaded the retrocecal appendix, causing acute appendicitis. Such a highly unusual occurrence has not been described in the English literature.
A malignant tumor of the submandibular gland was found to consist predominately of spindle cell elements that initially suggested a primary sarcoma. Further examination revealed that the spindled malignant cells were derived from a high-grade mucoepidermoid carcinoma.
A large single renal cyst occurring in a 56-year-old man was found to be a cystic renal cell carcinoma on surgical exploration. Various diagnostic tests preoperatively did not reveal the true nature of the cyst.
A 54-year-old-man presented with inferior vena caval obstruction. At autopsy, a retroperitoneal malignant fibrous histiocytoma was noted to have invaded the inferior vena cava. Such a clinical presentation is quite unusual for a retroperitoneal sarcoma.
This report describes a 60-year-old woman with a fibroma of tendon sheath of left hand. Ultrastructural study of the tumor reveals the nature of the tumor cells as fibroblasts, thus distinguishing it from the more common giant cell tumor of tendon sheath believed to be derived from synovial cells.
Twenty-nine cases of lung cancer occurring in men aged 40 or less were examined at autopsy. Histologic types of cancer and metastatic patterns in this group of patients were similar to those seen in middle-aged or elderly patients except for a lower occurrence of lymphatic spread in the younger group.
A case of symptomatic granular cell tumor of the esophagus is described. Another 32 cases collected from the English literature are analyzed. The reported cases have occurred mostly in women of less than 50 years of age presenting with dysphagia. Excision of the lesion is curative.
A case of human sparganosis is reported. Approximately sixty-eight such cases have been reported from the United States, most having been found in the southern states. Clinically sparganosis appears as a subcutaneous nodule. Diagnosis is established after the larval worm has been identified in the excised tissue. Excision of the lesion is curative.
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We describe a case of renal cell carcinoma with metastasis to the penis clinically presenting with priapism. Six such cases found in the literature are reviewed. Neoplastic disease is far advanced in these cases and therapy is only palliative.