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Biomedical subjects

D Oth

Publications and source records attributed to D Oth.

At least 73 records · Page 4Linked to original sources
PubMed1975

Tumor-associated antigens in isoantigenic variants of a 3-methylcholanthrene-induced sarcoma.

A sarcoma was induced in an (A.CA X A.BY)F1 mouse. Two isoantigenic variants were selected by loss of one H-2 antigen. The tumor-associated transplantation antigens (TATA) of these variants were compared as to their specificities in (A.CA X A.BY)F1 mice. Both transplantation and indirect membrane immunfluorescence tests revealed that TATA of both variants did not cross-react. Thus selecting angainst different H-2 antigens also selected different TATA. Karyotype studies suggested that both variants originated from a unique clone.

Animals↗
PubMed1975

Current questions on the tumour-associated antigens of chemically-induced tumours. I. In search of their characterization.

The main methods for detecting the tumour associated antigens of chemically-induced tumours, and the significance of the results given by these methods are briefly reviewed. The possibility of finding several sorts of tumour antigens is discussed more specifically. The origin of the antigenically unique (non-crossing) antigens found in the chemically-induced tumours, as compared to the frequently cross-reacting antigens found in the virus-induced tumours, gives rise to speculation. The biological significance of these antigens is discussed.

Antigens, Neoplasm↗