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Biomedical subjects

D Onicescu

Publications and source records attributed to D Onicescu.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Histoenzymatic activity of leucine aminopeptidase in normal bone marrow cells.

Human, monkey, cat and rat bone marrow cells were studied for the histochemical localization of leucine aminopeptidase activity. The granulocytes have a weak enzymic activity in the immature cells and a very strong one in the differentiated cells. The lymphopoiesis is characterized by a strong reaction in the lymphoblasts and different degrees of the enzyme activity in the lymphocytes. In the erythropoiesis, the undifferentiated cells are strongly positive, while the erythrocytes are negative. The immature and mature cells of the megakariocytic line show a weak leucine aminopeptidase activity.

Age Factors↗
PubMedDate not supplied

Histoenzymological study on desquamative cervico-vaginal cells.

Dihydrofolate dehydrogenase activity was histochemically investigated comparatively to the activities of 6-phosphogluconate, glucose-6-phosphate, malate and lactate dehydrogenases, NADH-2-tetrazolium dehydrogenase, esterases, beta-glucuronidase and leucyl aminopeptidase in smears of desquamative cervico-vaginal cells of negative and positive Papanicolaou classes. Dihydrofolate dehydrogenase was found active in a greater percentage of cells and stronger in individual cells of cervical carcinoma than in normal, inflammatory or dysplastic cervix uteri. The other enzymes activities were less specifically increased in dyskaryotic cells.

Carcinoma, Squamous Cell↗