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Biomedical subjects

D O Mikaelian

Publications and source records attributed to D O Mikaelian.

At least 19 recordsLinked to original sources
PubMed1991

Lipoinjection for unilateral vocal cord paralysis.

Injection of Teflon paste is a commonly accepted procedure to improve the caliber of voice in unilateral vocal cord paralysis. There are several drawbacks to Teflon injection, among them respiratory obstruction (from overinjected Teflon) and unsatisfactory voice quality (Teflon causes stiffness of the vocal folds). This paper is a preliminary report on lipoinjection instead of Teflon injection into a paralyzed vocal fold. Fat appears to impart a soft bulkiness to the injected cord, while allowing it to retain its vibratory qualities. It is autologous material and can be retrieved if excessively overinjected. The fate of autologous fat injected into a paralyzed vocal cord remains unknown. Most of the literature on lipoinjection concerns repairs of depressed scars or breast augmentation. Our longest follow-up has been 12 months. Three patients have had this procedure, and the results appear to be very encouraging.

Abdominal Muscles↗
PubMed1989

Hypoglossal nerve paralysis.

The hypoglossal nerve is frequently involved in head and neck afflictions as a result of its long course. Hypoglossal nerve paralysis, rarely occurs as the initial presenting symptom. Clinical situations, where the hypoglossal nerve paralysis was an early symptom, are discussed. The anatomy of the nerve from the brain stem to the tongue is elaborated upon.

Adult↗
PubMed1986

Brainstem auditory evoked potentials in fullterm and preterm newborns with hyperbilirubinemia and hypoxemia.

Brainstem auditory evoked potentials (BAEP) were studied in 93 newborns (49 preterm and 44 fullterm) admitted to the neonatal intensive care unit. One group of 42 infants (28-42 wk CA) were considered at low risk for perinatal complications and served to establish the normal ranges of the BAEP parameters (wave I peak latency and wave I-V interwave interval). Two groups of high risk infants were studied during or shortly following clinically significant hyperbilirubinemia (31 infants) or hypoxemia (20 infants). Though statistically significant BAEP abnormalities were found in the high risk infants, these consisted predominantly of wave I latency prolongations in hypoxemic infants (p less than 0.05) indicating dysfunction in peripheral auditory processes. No significant increases in the wave I-V interval (central conduction time) were found in the high risk infants to suggest central auditory dysfunction in the brainstem. These findings are discussed in relation to previous studies of hyperbilirubinemic and hypoxemic infants.

Brain Damage, Chronic↗
PubMed1986

Epithelial-myoepithelial carcinoma of the subglottic region: a case presentation and review of the literature.

Epithelial-myoepithelial carcinomas are a rare form of salivary gland carcinoma. They are found predominantly in the parotid glands and rarely occur in the upper airway and in minor salivary glands. These neoplasms are found predominantly in women in the seventh and eighth decades of life and account for less than 1% of all salivary gland ductal carcinomas. These tumors may demonstrate infiltrative and destructive patterns, with a tendency to metastasize. It is recommended that they be approached and treated along the same avenues as any other malignant lesions of the head and neck.

Adult↗
PubMed1986

Perichondrial-cartilage island graft in one stage tympano-ossiculoplasty.

A one stage reconstruction of the tympanic membrane and the ossicular chain using a composite graft of tragal perichondrium with cartilage is described (Type III tympanoplasty). The long-term results in 18 operated cases reveals closure of the air-bone gap to within 0 to 10 dB in 72% of the cases. The above procedure used autologous graft material, does not disturb the remaining middle ear structures, can be performed under local anesthesia, and in most cases is done on an outpatient basis.

Adolescent↗
PubMed1985

The vestibular aqueduct syndrome: computed tomographic appearance.

We have recently examined three young patients with congenital unilateral profound sensorineural hearing loss. On computed tomography the only abnormality discovered was a remarkably enlarged vestibular aqueduct on the abnormal side. The vestibular aqueduct syndrome is an important cause of congenital hearing loss. Although this finding has been well illustrated with conventional multidirectional tomography, there has been little emphasis on the computed tomographic appearance.

Adult↗
PubMed1984

Reconstruction of the tongue.

Subtotal or total glossectomies performed for malignancies or other afflictions of the tongue are fraught with great disabling problems postoperatively. Recently the introduction of myocutaneous flaps has aroused new interest in surgical procedures to reconstruct the tongue following major resections. A new approach to functional reconstruction of the tongue is presented utilizing the sternocleidomastoid myocutaneous flap based superiorly. Neurorrhaphy between the hypoglossal nerve on the resected side of the tongue and the nerve to the sternocleidomastoid muscle is easily achieved without under tension as these nerves are in close proximity. In addition, the sternocleidomastoid myocutaneous flap is an ideal flap in tongue reconstruction as there is no fat between the skin and muscle and it resembles the bulkiness of the tongue muscle itself. A patient with a carcinoma of the tongue treated with subtotal resection and reconstruction using the above principles demonstrated full tongue movements 11 months postoperatively.

Glossectomy↗
PubMed1983

Bell's palsy.

Explore the source record for details and available documents.

Facial Paralysis↗