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Biomedical subjects

D O Hammond

Publications and source records attributed to D O Hammond.

14 recordsLinked to original sources
PubMed1980

Effects of dilute acetic acid on cancer cytology. I. Effects on normal tissue.

The simultaneous use of exfoliative cytology and colposcopy is occasionally indicated in the detection of cervical cancer. When there is a fragile epithelium in the perimenopausal or postmenopausal woman, the taking of a cytology preparation may cause sufficient vascular injury so that subsequent colposcopy is not possible. A series of patients was subjected to primary colposcopy followed by cytologic testing in order to evaluate the effect of dilute acetic acid on the Papanicolaou preparation. The minimal alterations caused by dilute acetic acid are easily recognized and do not impair the validity of the cytologic technique for cancer detection.

Acetates↗
PubMed1977

Cytological assessment of climacteric patients.

The cytohormonal method using the upper lateral vaginal wall is an inexpensive, rapid, painless, effective and simple technique for measuring hormone effect in the human. With proper safeguards, one can evaluate the proliferative effect of oestrogens. The astute experienced clinician can use this test as one of several parameters to study the menopause and some of its related metabolic and neoplastic conditions. The cytohormonal proliferated condition (KI) cannot, and should not, be used as the only criterion for diagnosis and therapy. The presence of cells showing low levels of proliferation would be a valid measure of oestrogen lack and clinical need. This evaluation of the low end of the proliferation scale (low intermediate and parabasal cells) would more likely be useful and certainly more consistent with cytohormonal reality.

Androgens↗