Nasopharyngeal angiofibroma.
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Biomedical subjects
Publications and source records attributed to D O Davis.
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Health care reform has made quality efficacy research in MRI important to an increasing number of audiences. Historically, the deficit of quality outcomes research in MRI was due to difficulties in study design, lack of funding, disincentives for researches and funding sources, and poor coordination. These issues would be best addressed by the formation of an MRI implementation group that would coordinate funding, planning, and dissemination of the outcomes research efforts.
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Computerized tomography during the past few years has been unequivocally been proven to be of extreme value in the evaluation of intracranial disease. Despite earlier reports, accuracy of diagnosis in the area of the sella turcica is found to be high despite the close proximity of both bony and air-containing structures. Correlation between computed tomographic images, angiography and pneumoencephalography has been performed and demonstrates that CT scans with a low margin of erro depict the relationships of pituitary adenomas to the surrounding brain parenchyma. The continued importance of angiography, and to some degree pneumoencephalography, in the diagnosis of pituitary tumors is discussed.
Fundamental image descriptors, including contrast, noise, and resolution, were appropriate for computed tomography. These variables were then used to predict limiting system performance as applied to a model for detection of simple tumor-like signals in a homogeneous surround. The results predict that any intrinsic physical advantages of computed tomography may be restricted to a fairly narrow range of tumor diameters, from a few millimeters to a few centimeters, depending on the relative dose levels and scatter levels present in each imaging system. The results indicate high probable yield for radiographic image manipulation involving independent or, preferably, mutual manipulation of scatter levels, contrast enhancement, kVp techniques, and subtraction techniques, where applied to reduce the highly structured backgrounds that can increase the complexity of diagnosis.
Diagnostic quality and adverse reactions associated with metrizamide and iohexol as contrast agents for lumbar myelography were compared in a prospective randomized double-blind study in 350 patients at seven centers. Both contrast media were administered in comparable volumes at a concentration of 180 mg I/ml. Overall quality of radiographic visualization was graded as "good" or "excellent" in 95% of 175 metrizamide studies and in 98% of 175 iohexol myelograms. Ninety-three patients examined with metrizamide (53%) and 130 patients studied with iohexol (74%) experienced no discomfort during or after myelography. The incidence of postmyelographic headache was 38% with metrizamide and 21% with iohexol. Nausea and vomiting were also more common with metrizamide. Five patients examined with metrizamide (3%) experienced transient confusion and disorientation after lumbar myelography. No such reactions were observed after iohexol myelography.
Two cases of a rare entity, Candida diskitis, are reported with presentation of plain film and CT findings. Guidelines for diagnosis and treatment are reviewed.