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Biomedical subjects

D Nunns

Publications and source records attributed to D Nunns.

31 records · Page 2Linked to original sources
PubMed1995

Wilson's disease in pregnancy.

Patients with Wilson's disease contemplating pregnancy should have their hepatic function and copper status assessed. We report a case of a pregnant woman with Wilson's disease with compromised hepatic function. The medical problems and controversy of prescribing treatment are discussed.

Adolescent↗
PubMed1995

Reagent strip testing urine for significant bacteriuria in a urodynamic clinic.

OBJECTIVES: To determine the effectiveness of two reagent strips in detecting significant bacteriuria amongst patients attending for urodynamic assessment. PATIENTS AND METHODS: Four hundred patients undergoing urodynamic assessment were recruited for the study. Routine diagnostic catheter specimens of urine were tested for nitrite, leucocytes and protein. RESULTS: The leucocytes and nitrite strips had a high specificity rate of 99.5%. The frequency of significant bacteriuria in our population was 7% (n = 28). CONCLUSION: Culturing samples which test negative for these strips is unnecessary. Reagent strip testing of urine provides a cheap, rapid method of screening for infection.

Ambulatory Care↗
PubMedDate not supplied

Guidelines for gynecological cancer-an audit of current network documents in England and Wales.

The objective of this study was to assess the adequacy of network cancer guidelines paying particular attention to referral criteria, referral routes, tumor diagnosis, staging, and suggested management and care pathways for ovarian and endometrial cancer. Guidelines from 15 regions in England and Wales were analyzed quantitatively and qualitatively as a prospective audit of predefined data items and subsequently agreed management recommendations. Details of unit and center clinicians were included in a minority of documents (2 to 5/15). Multidisciplinary team membership was not usually offered (6/15). Among the least reported data items were histopathology minimum dataset for endometrial cancer and an algorithm for management or summary and clinical symptoms and signs for both cancers. Among the most reported data items were hysteroscopy and ultrasound scanning for endometrial cancer and CA125 and chemotherapy for ovarian cancer. Qualitative analysis revealed differing criteria for the use of endometrial biopsy and radiotherapy in endometrial cancer, for lymphadenectomy and management of recurrent disease in ovarian cancer, and for referral pathways and the use of computed tomography/magnetic resonance (MR) scanning in the assessment of either disease. This study concludes that consideration should be given to the development of national guidelines or templates to ensure consistency of management for gynecological malignancy in England and Wales.

Female↗