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Biomedical subjects

D Norris

Publications and source records attributed to D Norris.

90 records · Page 5Linked to original sources

The weeping ear: clinical re-evaluation of treatment.

This study was designed to compare the efficacy and safety of gentamicin otic solution versus colistin-neomycin-hydrocortisone otic suspension in the treatment of otorrhoea due to infection. Fifty-five patients (mean age 36.6 +/- 22.1 years) with sixty infected ears with otorrhoea complicating otitis externa, recurrent otitis media with tympanic membrane perforation, or infected mastoid cavities and post-operative tympanoplasties, were treated for 14 days with either an aqueous solution of gentamicin 0.3% or an aqueous suspension of colistin 0.3%, neomycin 0.33% and hydrocortisone 1.0%. The two possible treatments were assigned randomly and the results were assessed double-blind using usual ordinal scales for monitoring the severity of symptoms. Both otic preparations were found to be equally safe in the treatment of otorrhoea due to infection. No side-effects were observed and hearing status was either unchanged or improved. The antibiotic-steroid combination appeared to be more effective in relieving inflammation in a shorter period of time while gentamicin was observed to be more effective in eradicating the infecting organisms.

Adult↗

Actinomycosis of the gallbladder.

Actinomycosis of the gallbladder is rare, and the pathogenesis of the infection is poorly understood. The authors report the case of a 77-year-old man admitted to hospital because of abdominal pain. Clinical and laboratory findings suggested the diagnosis of cholecystitis and cholelithiasis. At cholecystectomy the gallbladder was inflamed and contained many calculi. Gram staining of material from the mucosa of the gallbladder demonstrated gram-positive pleomorphic filaments, and Actinomyces israelii grew in pure culture, thus confirming the diagnosis of actinomycosis of the gallbladder. The pathogenesis of the condition is also discussed.

Actinomyces↗

Family planning in Pakistan: an analysis of some factors constraining use.

Family planning efforts by the Pakistan government were greatly expanded during its third Five-Year Plan (1965-70). Cross-sectional data obtained from the 1968-1969 IMPACT Survey are analyzed to determine the relative importance of demand and availability factors in explaining the response of Pakistani couples to the program's efforts. The findings indicate that the proportion of couples who express interest in controlling their fertility in the future is larger than the proportion who report current use of a family planning method. The analysis, however, shows that the program delivery system did not reach most of those who indicated they were potential users. When adequate availability was reported, family planning was adopted despite existing traditional social constraints; nonetheless, the analysis also points out that the potential of the program was severely limited by these constraints.

Delivery of Health Care↗

A language-specific comprehension strategy.

Infants acquire whatever language is spoken in the environment into which they are born. The mental capability of the newborn child is not biased in any way towards the acquisition of one human language rather than another. Because psychologists who attempt to model the process of language comprehension are interested in the structure of the human mind, rather than in the properties of individual languages, strategies which they incorporate in their models are presumed to be universal, not language-specific. In other words, strategies of comprehension are presumed to be characteristic of the human language processing system, rather than, say, the French, English, or Igbo language processing systems. We report here, however, on a comprehension strategy which appears to be used by native speakers of French but not by native speakers of English.

Hearing↗

Intravenous immune globulin for patients alloimmunized to random donor platelet transfusion.

Immune globulin, prepared as a chemically and enzymatically unmodified solution in 10 percent maltose at pH 4.25, was administered intravenously, at a dose of 0.4 g per kg per day for five consecutive days, to seven alloimmunized patients who had acute nonlymphocytic leukemia. All patients had an approximately threefold rise in IgG level. Five patients showed no change in lymphocytotoxic antibody (LCTAb) activity and no response to random donor platelets that were administered after the immune globulin. The activity of LCTAb either disappeared or diminished after immune globulin infusion in two patients, and they had borderline acceptable corrected count increments 1 hour after transfusion of pooled random-donor platelet transfusions. Because of the diminished LCTAb activity, the improvements in response to pooled random-donor platelet transfusions cannot be ascribed to the administration of immune globulin. High-dose intravenous immune globulin has not been shown to be effective in reversing the effects of alloimmunization.

Acute Disease↗

Expanding the guidelines for electronic communication with patients: application to a specific tool.

In 1998, the American Medical Informatics Association (AMIA) published a white paper entitled "Guidelines for the Clinical Use of Electronic Mail with Patients," which outlined a practical framework for this interaction. Interest in the use of other Internet-based tools, such as the World Wide Web, to enhance clinical communication is increasing. In such systems, static information can be made centrally available to patients and interactive tools such as messaging systems, schedules, and individualized care regimens can be integrated within the site. Site-specific guidelines are needed to address potential problems inherent in the particular services being offered. This article presents advice on developing site-specific guidelines, with examples, based on experience gained in developing and refining guidelines for the use of PatientWeb at the Massachusetts General Hospital Department of Neurology.

Computer Communication Networks↗

The bispectral index monitor: a new tool for air medical personnel.

The bispectral index monitor (BIS) is commonly used in the operating room to help anesthesiologists quantitate the level of anesthesia. The BIS has been shown to reduce the incidence of anesthetic overuse and decrease costs. The device has made its way into critical care areas, where it has proven effective in monitoring sedation levels, specifically in reducing the incidence of oversedation. This article explores the possibility of using the monitor in the air medical environment.

Air Ambulances↗

Independent means.

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Female↗