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Biomedical subjects

D Nenov

Publications and source records attributed to D Nenov.

28 records · Page 2Linked to original sources

[Acute renal insufficiency in poisoning with cistol (carbon tetrachloride)].

Three cases of acute intoxication with the preparation "Cistol", containing tetrachloro-methane were described, with the development of acute renal insufficiency, treated with hemodialysis. The attention of the physicians and the society is drawn to the risk of intoxication by that preparation. Early hemodialysis is recommended in case of such intoxications.

Acute Kidney Injury↗

[Changes in the alkaline-acid status and some plasma electrolytes in chronic hemodialysis patients].

Prior to and post hemodialysis, a determination of plasma potassium, sodium, calcium, phosphorus and the indices of acid-base state is performed in 16 patients with chronic terminal renal insufficiency, with 560 hemodialyses, applied once or twice a week with deionized water and dialysis solution with 1, 5 mEq/1 potassium. Considerable hypopotassemia was established after hemodialysis--3, 3 mEq/1 and in 35% of the cases--hypopotassemia under 3.0 mEq/1. Metabolite alkalosis was established after dialysis: elevated pH in blood from 7,353 to 7,491; standard bicarbonates--from 21, 2 to 29, 1 m Eq/1; basis-excess: from (-3, 78) to (+5, 26) mEq/1; buffer bases: from 41, 3 to 51, 0 Eq/1, normalization of the elevated phosphorus in plasma from 7, 4 mg% to 4, 6 mg%. No significant changes in plasma sodium and potassium, as well as pCO2 were established after hemodialysis.

Acid-Base Equilibrium↗

Combined treatment of immune nephropathies with plasmapheresis and immunosuppressants.

The treatment of patients with immune nephropthies is discussed: rapidly progressive nephritis, lupus nephropathy, Wegener granulomatosis, Goodpasture syndrome, Schonlein-Henoch nephritis. A combined treatment of plasmapheresis and immunosuppressants is applied. A definite result, specially with the cases of Wegener granulomatosis, is registered for certain number of the patients. Together with the usual tests: CIC, immunoglobulins, complement, etc. a method for controlling of the detoxic efficiency of the treatment is suggested. This is a biologic method- the level of paramecium caudatum in media from patients' plasma is registered in relation to time. After plasmapheresis the life of paramecium caudatum is considerably prolonged.

Adolescent↗