Platelet adhesiveness in postoperative deep-vein thrombosis.
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Biomedical subjects
Publications and source records attributed to D Negus.
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The effectiveness of a 72 h. intra-arterial prostacyclin infusion has been compared to that of naftidrofuryl oxalate (Praxilene) in a double blind study of 29 patients with ischaemic rest pain in 30 legs. Long-term relief of symptoms was achieved in 14 legs (47%) and major limb amputation avoided in 18 (60%). No significant difference was demonstrated between the results of prostacyclin infusion and those of Praxilene.
Long strippings (groin to ankle) are subject to an unacceptable percentage (23-58%) of neurological complications due to traumatism of the saphenous nerve. A simple saphenofemoral ligation avoids these complications, but the incidence of varicose relapse is nevertheless still about 60%. Our long saphenal strippings practised on 96 legs in 71 patients were followed in 4.2% by saphenous neurological symptoms, with varicose relapse in 12.5%; this is half as many as in sclerosant injection therapy.
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