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Biomedical subjects

D Negus

Publications and source records attributed to D Negus.

At least 55 records · Page 3Linked to original sources

Intra-arterial prostacyclin compared to Praxilene in the management of severe lower limb ischaemia: a double blind trial.

The effectiveness of a 72 h. intra-arterial prostacyclin infusion has been compared to that of naftidrofuryl oxalate (Praxilene) in a double blind study of 29 patients with ischaemic rest pain in 30 legs. Long-term relief of symptoms was achieved in 14 legs (47%) and major limb amputation avoided in 18 (60%). No significant difference was demonstrated between the results of prostacyclin infusion and those of Praxilene.

Aged↗

[Should the incontinent saphenous veins be stripped down to the ankle?].

Long strippings (groin to ankle) are subject to an unacceptable percentage (23-58%) of neurological complications due to traumatism of the saphenous nerve. A simple saphenofemoral ligation avoids these complications, but the incidence of varicose relapse is nevertheless still about 60%. Our long saphenal strippings practised on 96 legs in 71 patients were followed in 4.2% by saphenous neurological symptoms, with varicose relapse in 12.5%; this is half as many as in sclerosant injection therapy.

Adult↗