Teicoplanin is a glycopeptide antibiotic which was introduced into clinical use in 1988. Its activity against most Gram-positive bacteria, including the emergent multiply resistant species, its ease of administration and safety commend its continued use well into the next millennium. The provision of health care in alternative settings such as the home or outpatient clinic has grown in importance, both in Europe and North America. One such service is the provision of parenteral antibiotics for treating a variety of infections in the non-inpatient setting. This paper aims to review and condense the current published experience of teicoplanin in this setting. Evidence suggests that teicoplanin can be administered effectively using a range of flexible, convenient and safe dosing schedules and is a highly cost-effective therapeutic option for treating in the non-inpatient setting many chronic infections e.g. osteomyelitis and endocarditis, and some acute infections.

Ambulatory Care↗

PubMedDate not supplied

Necrobacillosis revisited.

Explore the source record for details and available documents.

Adult↗

PubMedDate not supplied

Herpesvirus infections in childhood: 1.

Infections due to herpesviruses have received increasing attention over the past decade, culminating in the isolation in 1986 of human herpesvirus 6. We examine the clinical spectrum of acquired herpesvirus infections in children and review developments in our understanding of their molecular biology, pathogenesis, treatment and prevention.

Acyclovir↗

PubMedDate not supplied

Herpesvirus infections in childhood: 2.

Infections due to herpesviruses have received increasing attention over the past decade, culminating in the isolation in 1986 of human herpesvirus-6. This is the second of two articles in which we examine the clinical spectrum of acquired herpesvirus infections in children and review developments in our understanding of the molecular biology, pathogenesis, treatment and prevention of these infections.

Child↗

PubMedDate not supplied

Cryptococcal meningitis.

Fungal meningitis caused by the yeast Cryptococcus neoformans is most commonly seen in patients with defective T-lymphocyte function. This article focuses on the clinical presentation, diagnosis and management of patients with cryptococcal meningitis, in the setting of AIDS and other immunocompromised hosts, and in 'normal' individuals.

AIDS-Related Opportunistic Infections↗