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Biomedical subjects

D N Gupta

Publications and source records attributed to D N Gupta.

At least 37 records · Page 2Linked to original sources
PubMed1986

Studies on interventions to prevent eltor cholera transmission in urban slums.

Transmission of eltor cholera infection in endemic communities continues without diminishing because of the absence of effective intervention measures. Two methods-chlorination of stored water and the use of a narrow-necked earthenware vessel (called a 'sorai') for storing the water-were found to be effective in reducing the transmission of infection among the family contacts of cholera patients. The cholera carrier rates in the chlorination and 'sorai' intervention groups were 7.3% and 4.4%, respectively, compared with 17.3% in the control group. The 'sorai' is cheap and was well accepted by the local communities; its narrow neck prevented the introduction of the hand and contamination of the stored water.

Adolescent↗
PubMed1977

Contribution of lactic acid by the ampullary and isthmic parts of rabbit Fallopian tube under altered hormonal conditions.

The capability of the ampullary and isthmic parts of the rabbit Fallopian tube to contribute lactic acid (LA) to the tubal lumen was examined using an in vitro method of study. In addition concomitant study was also made using the uterus. It was found that in the oestrous rabbit, the isthmus contributed LA at a higher rate than that of the ampulla; the uterine contribution was minimal. Ovariectomy reduced while exogenous oestrogen enhanced this ability in all the three tissues. In mated post-ovulatory rabbits the contributory efficiency of either tubal part changed and appeared to exhibit a peak value in the presence of the ovum; the uterus showed no such changes. This is discussed in relation to the ability of the egg to secure its energy source until it attained morula/the pre-blastocyst stage.

Animals↗
PubMed1977

Incorporation of [U-C14-A1-glucose in vitro by different parts of the rabbit Fallopian tube and uterus.

The in vitro incorporation of E1U-C14]-glucose by ampullary and isthmic segments of the Fallopian tube and the uterus was determined in the intact (estrous), ovariectomized, ovariectomized plus estrogen and ovarietcomized plus estrogen + progesterone treated rabbit. In the intact animal the ampulla incorporated glucose at a faster rate than the isthmus; uterine uptake is minimal. Ovariectomy reduced the rate of incorporation below normal values in all the tissues. EDP (estradiol dipropionate) administered to ovariectomized rabbit increased the incorporation rate. Progesterone antagonized the EDP-induced uptake. The relative rate and pattern of incorporation by the three tissues were, however, determined by the dosage of estrogen and the estrogen/progesterone ratio.

Animals↗
PubMed1977

Differential response of the ampullary and isthmic cells to ovariectomy and estrogen treatment: an ultrastructural study.

Ultrastructural response of the ciliated and secretory cells from the ampullary and isthmic parts of the oviduct was studied in ovariectomized and ovariectomized plus estradiol dipropionate (EDP) treated rabbits. Ovariectomy did not significantly affect the cilia in the ampullary epithelium; degenerative signs, however, appeared overtly in the isthmic cilia. EDP at either 1 microng/kg or 5 microng/kg doses raised the number of cilia/cell in either tubal segments. For comparable change isthmic cilia seemed to require a higher dosage of the estrogen. Ovariectomy led to the depletion of the secretory granules (SGs) from the secretory cells of either tubal segments. EDP at both the doses induced formation of the SGs; this is more remarkable in the isthmic cells. Merocrine type of secretions were observed from the secretory cells of either segments but only at the high dose of estrogen. The findings are discussed in the backdrop of current knowledge.

Animals↗