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Biomedical subjects

D Musset

Publications and source records attributed to D Musset.

62 records · Page 4Linked to original sources
PubMed1981

[False image of renal artery aneurysm during intravenous urography. A previously unreported sign (author's transl)].

A rounded shadow of the renal sinus was observed, during the late vascular period of intravenous urography, in a true profile film of the kidney. Interpreted as being due to an aneurysm, a series of investigations were instituted, including more particularly angiography. It was finally demonstrated that the image corresponded to the segment of origin of a rectiliniar renal vein, seen axially. An observation of this type has not been previously reported, and raises certain questions on the practical attitude to adopt in such cases.

Adult↗
PubMedDate not supplied

In vivo evaluation of a retrievable vena cava filter--the Dibie-Musset filter: experimental results.

PURPOSE: To evaluate, in an animal model, the efficacy and safety of a 7 Fr percutaneous vena cava filter for temporary or permanent use. METHODS: The Dibie-Musset (DM) filter is a wire preformed into a double-spiral shape with a spring effect. The experiment was performed in 15 adult sheep and consisted of the insertion of 45 filters, clot trapping tests, and filter retrieval. Follow-up in all sheep consisted of radiologic (abdominal radiograph, inferior vena cavogram, abdominal computed tomography), macroscopic, and microscopic examinations between days 8 and 386 after filter placement. RESULTS: Of the 45 filters implanted in 15 sheep, 29 were retrieved between day 0 and day 15. Filtration efficiency was 100% for clots 4 x 4 x 20 mm. No long-term (1 year) side-effects were detectable. Microscopic examination of the vein wall showed only a dense intimal fibrosis without signs of acute inflammation at 1 year. CONCLUSION: These results support the efficiency and safety of the DM filter in an animal model.

Animals↗
PubMedDate not supplied

Role of CT in chronic pulmonary embolism: comparison with pulmonary angiography.

To assess the value of CT in chronic pulmonary embolism (CPE), CT scans and pulmonary angiograms of 21 consecutive patients were reviewed. Computed tomography was better than angiography in assessing proximal clots (three thrombi not seen by angiography, three angiographic false-positives confirmed by surgery). Furthermore, CT was able to analyze pulmonary arteries distal to angiographic amputations. Computed tomography was less sensitive than angiography for vascular distortions (38 vs. 50%) and stenosis (35 vs. 71.8%). Pulmonary infarctions were better detected and characterized by CT than by angiography. Isolated parenchymal ground-glass opacities were seen by CT in 18 patients, especially in those with right cardiomegaly. High resolution CT delineated them better than did standard CT. Computed tomography may be a useful adjunct to angiography in the assessment of CPE.

Adult↗
PubMedDate not supplied

[Embolization of hepatic metastases].

The results of 42 cases of arterial embolisation in patients with hepatic metastases are reported. In two-thirds of the cases the primary tumor was found in the gut. In eight cases endocrine tumor dissemination was incriminated. Arterial occlusion called for use of various inert substances (e.g. Spongel, Duremere) or cyanoacrylate, but in this instance chemical embolisation was excluded. The antalgic effect of embolisation (72 percent success rate) and antipyretic effect on persistent fever (60 percent success rate) constituted the usual indications. Metastases of secreting tumors are verily more rare, nevertheless they are indubitably a major indication for embolisation, since good results are achieved concerning inopportune secretions and repeat embolisations possible are a super advantage. The good symptomatic results of embolisation must incite its consideration in unoperable but nonterminal cases whose medical therapy is no longer or simply not effective.

Adult↗
PubMedDate not supplied

[Multicystic renal dysplasia, peculiar developmental aspects: spontaneous remission followed-up by ultrasonography. Apropos of 2 cases].

Two cases of unilateral multicystic kidney followed an atypical course, the non-communicating anechogenic images on ultrasound examination that projected into the renal region disappearing within several months and the infants' condition appearing satisfactory at 2-year follow up review. Analysis of the literature showed the increasing frequency of this outcome, but persistence of a multicystic kidney after the first year of life requires its surgical removal because of risk of degenerative changes.

Female↗
PubMedDate not supplied

[Percutaneous caval filter Dibie-Musset "DM". Results of animal experiments].

AIM: a 7 F percutaneous cava filter was achieved, developed and tested in a goat. Thanks to its double-spiral original form, it is possible to place and remove it atraumaticaly and percutaneously. PRINCIPLES OF THE FILTER: its diameter, larger than the lower vena cava's (LVC) leads to a flattening of the venous lumen whose flow is intersected by the filter turns, thus creating a netting effect. CASE-REPORT: during 28 months, 40 filters were introduced under fluorscopy in 20 goats. Thanks to 16 embolizations, it was possible to test the effectiveness of the filter against small emboli, with simultaneous cavography and pulmonary angiography in 4 cases. 29 filters were removed by jugular and femoral track, from D0 to D14. 12 goats were sacrificed to investigate histologicaly and macroscopicaly the LVC and control the biocompatibility from the 8th to the 385th day. Clinical and radiological supervision lasted more than one year for 3 goats. RESULTS: the size of the filter (30, 35, 40 mm) is chosen from the LVC diameter measured by cavography. 30 filters were introduced via jugular vein, 10 via femoral vein. These filters were introduced by catheter 7F thanks to an applicator and placed in correct position in the LVC. RELIABILITY OF THE FILTER: easy percutaneous introduction 7F. Once installed, the filters flatten the LVC; this process is automatically confirmed by cavography, and by scanning in 4 cases. EFFECTIVENESS AGAINST EMBOLI: out of 16 cases, 2 partial failures were observed at the beginning of the experiment (one spiral-fitted filter). Its effectiveness was optimized thanks to the addition of a second spiral which allowed the blocking of over-2 mm clots. PERCUTANEOUS REMOVAL: during the initial removals, partial failures were due to the fragility of the filter and the inflexibility of the extracting material. Successive changes of the shape and the alloy of the filter as well as the development of catheters and extracting materials have led to a sufficient reliability to remove (D0 to D14) the filter in security, by percutaneous tract (9 jugular, 9 femoral) before its clamping on the LVC, on the 15th day. INNOCUOUSNESS: both biological supervision and anatomo-pathological investigation have showed the good tolerance of the filter. In local areas, this atraumatic filter does not wound nor perforate the LVC wall. Histologically, a thickening of the intima is observed. The positive results of this experiment led us to start clinical trials of "DM" filter in human beings.

Angiography↗