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Biomedical subjects

D Moore

Publications and source records attributed to D Moore.

385 records · Page 22Linked to original sources
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Phase I study of anguidine administered weekly.

Anguidine was administered on a weekly schedule to 20 patients. Gastrointestinal and neurologic toxic effects were dose-limiting for both 4- and 8-hour infusions of anguidine. Myelosuppression was infrequent and not dose-related. Recommended starting doses for weekly anguidine are 6.0 mg/m2 for patients with normal hepatic function and 3.5 mg/m2 for patients with liver dysfunction.

Antineoplastic Agents, Phytogenic↗
PubMedDate not supplied

Prepared childbirth and marital satisfaction during the antepartum and postpartum periods.

A longitudinal study of 105 couples, this study addresses whether there is a change in marital satisfaction throughout the perinatal period and whether any changes in the marriage or the labor and delivery might be attributable to the type of preparation for childbirth engaged in by the couple. Analysis of the demographic variables indicated that the groups were very similar. The only difference was that the Lamaze women had 16 years and the hospital-instructed women had 15 years of education (p less than 0.048). ANCOVA analysis indicated that there was not a significant difference in the couple or female score from the 24-28 weeks of pregnancy to 3-21 days postpartum, but there was a significant difference (p less than 0.04) in the male score after taking Lamaze vs. hospital-based classes. With both the husbands and wives there was an improvement in the marital satisfaction from 24-36 weeks of pregnancy to 3-21 days postpartum. When the initial level of marital satisfaction was controlled statistically, no correlation was found between the couples marriage score and the male and female years of education, age, SES, length of labor, medication in labor, and choice of rooming-in. The labor variables indicated that the Lamaze group had a slightly longer labor than the hospital group, but they used significantly less medication (p less than 0.05) and chose rooming-in more often (p less than 0.06).

Adolescent↗
PubMedDate not supplied

Results and lessons to be learned from a waiting list initiative.

Varicose veins are a major and increasing burden on the health service with waiting lists growing in the majority of units. Most successive Governments have funded waiting list initiatives to deal with this problem. We report the results of a one year varicose vein waiting list initiative which dealt with a total of 1104 patients. A standard triage regime was established. Two hundred and eighty five patients were removed from the waiting list due to failure to attend, surgery performed elsewhere, medically unfit or no longer wishing to have surgery. There were 63 late cancellations and 23 operations were cancelled following admission due to unrelated medical complications. Planned operating lists worked well and complications were uncommon. Several important lessons were learnt during this initiative and recommendations are made with regard to the optimal method of dealing with the problem of varicose veins.

Delivery of Health Care↗