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Biomedical subjects

D Michel

Publications and source records attributed to D Michel.

329 records · Page 19Linked to original sources
PubMedDate not supplied

[Sneddon syndrome: 9 cases].

We observed a series of 9 patients (1 male, 8 females, mean age 49 years) who had experienced cerebral vascular events with livedo racemosa (Sneddon's syndrome). Vascular dementia occurred in 3 patients and in the 6 others there was a single or several acute cerebral ischaemic events. Angiography of the brain revealed multiple distal arterial occlusions in 5 cases and a moya-moya type collateral network in 2. Positivity for anticardiolipid antibodies fluctuated in 4 cases and there was a lupic syndrome in 2. Systemic lupus erythemosus was diagnosed in the last patient. Mitral valve defects were seen in 5 patients, including 3 due to post-rhematitis sequelae which became symptomatic before the appearance of signs of neurocutaneous involvement. Among these three patients, laboratory tests revealed a lupus band in one, anticardilipid antibodies in another and obliterating fibrous endartiritis of the renal arteries in the third. Sneddon's syndrome presents with heterogeneous signs related to its complex pathophysiology.

Antibodies, Anticardiolipin↗
PubMedDate not supplied

[Memory complaints and anxiety. Apropos of 40 patients attending a specialized memory consultation].

This study reports results of the specialized memory consultation based on 2 successive examinations, one by a neurologist, the other by a psychologist, of 40 anxious subjects with or without social phobias. Traumatic events were frequent and we observed Alzheimer's disease in the family of 41.9% of subjects. Anxious subjects obtained a high score in Mac Nair questionnaire [44.05 (16,49)]. Their principal complaints were attentional difficulties. They obtained normal but low performances for free recall of 10 pictures, logical memory (QM), and inverse span. Mac Nair score was only correlated with logical memory score. Standardized psychometric evaluation showed short-term memory difficulties. Attention seems to be unstable and anxious individuals have relatively limited attentional resources. They are preoccupied by their anxiety and thus have less ability to focus on tasks.

Adult↗