Biomedical subjects

D Metze

Publications and source records attributed to D Metze.

112 records · Page 7Linked to original sources

PubMed1989

[Femorogluteal manifestation of lymphogranuloma venereum].

We report on a case of lymphogranuloma venereum in a 40-year-old man who acquired the disease while on vacation in Tunisia. After 4 years, a fibrosing, fistulating inflammation developed in an atypical distribution that involved the scrotum, perineum, and left gluteal and upper femoral regions; the disease progressed because of insufficient therapy. The diagnosis was established on serological examination, and treatment with doxycycline (2 x 100 mg for 4 weeks) improved the chronic inflammatory process.

Adult↗

PubMed1988

Disseminated superficial porokeratosis and immunosuppression.

We present a patient who developed skin lesions typical of disseminated superficial porokeratosis (DSP) while on immunosuppressive therapy for pemphigus foliaceus. Phototesting with artificial light sources did not have any effect on the DSP lesions. The literature describing occurrence of DSP on immunosuppression is reviewed and possible pathogenetic mechanisms are discussed.

Aged↗

PubMed1988

[Pigmented neurofibroma].

In a 24-year-old male melanin synthesis was demonstrated in a neurofibroma by light and electron microscopy. Although it is unclear whether the tumor cells are pigment-synthesizing Schwann cells or whether they originate from a coexisting melanocytic tumor, this tumor again demonstrates the close relationship between peripheral nerve sheath tumors and melanocytic malformations, as for example cellular blue nevi.

Adult↗

PubMed1986

[Immunoglobulin A in the sebaceous glands. Light and electron microscopy immunomorphologic detection].

This paper presents evidence for the presence of immunoglobulin A in human sebaceous glands. Light- and electron-microscopic immune cytochemistry techniques revealed secretory IgA in normal sebocytes and within pilosebaceous ducts. The secretory process corresponds to the well-established production of IgA at the site of other internal body surfaces. Basal and suprabasal sebocytes contain IgA in linear extracellular, as well as aggregated intracellular patterns. However, maximal diffuse concentrations are present at the opening of the pilosebaceous duct. This distribution pattern indicates an antimicrobial protective character of IgA, corresponding to similar functions on mucous membrane surfaces. Thus, another important humoral factor contributing to the complex system of skin-associated lymphoid tissue is postulated.

Acne Vulgaris↗