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Biomedical subjects

D Maxwell

Publications and source records attributed to D Maxwell.

At least 55 records · Page 3Linked to original sources
PubMed1987

Laryngeal manifestations of drug induced lupus.

Respiratory stridor and hoarseness were the predominant presenting symptoms in a 63-year-old woman with an hydralazine induced lupus syndrome. Laryngeal tomograms and direct laryngoscopy were consistent with cricoarytenoid arthritis. Proteinuria, anemia, arthritis, and leukocytoclastic vasculitis, as well as the laryngeal findings, all resolved after withdrawal of hydralazine. Laryngeal manifestations of systemic lupus erythematosus are reviewed.

Female↗
PubMed1986

Transabdominal chorionic villus sampling.

Transabdominal chorionic villus sampling, carried out with a fine-bore needle and cannula under ultrasound guidance, was as successful as transcervical aspiration but avoided the risks of bacterial contamination associated with the latter technique. The transabdominal procedure can be carried out under local anaesthesia, and multiple samples can be obtained, if necessary, through a single cannula.

Abdomen↗
PubMed1986

False positive localisation of indium-111 granulocytes in colonic carcinoma.

Indium-111 leucocyte scanning has been shown to be a highly accurate technique for detecting abscesses and assessing inflammatory bowel disease. We have encountered two cases of colonic carcinoma which presented as suspected inflammatory bowel disease and were found to localise 111In-labelled granulocytes. Histology revealed an acute inflammatory infiltrate in these tumours. These results indicate that 111In granulocyte scanning has limitations in the diagnosis of inflammatory bowel disease.

Aged↗
PubMed1985

Retinal vascular autoregulation in conditions of hyperoxia and hypoxia using the blue field entoptic phenomenon.

Autoregulation of retinal blood flow was studied in seven normal volunteers. The stimuli to autoregulation used were hyperoxia and hypoxia under controlled conditions of isocapnia. Macular blood flow was measured using the blue field entoptic phenomenon, and retinal artery and vein diameters were measured using a computerized digitising system. Results under conditions of isocapnic hypoxia showed a 38% average increase in blood flow and an increase in diameter of 8.2% and 7.4% in retinal arteries and veins, respectively. In hyperoxia, blood flow fell by an average of 36% and retinal artery and vein diameter decreased by 5.6% and 10%, respectively.

Adult↗
PubMed1985

A practical assessment of ultrasound-guided transcervical aspiration of chorionic villi and subsequent chromosomal analysis.

Aspiration biopsy of trophoblastic villi was performed on 56 patients immediately preceding suction termination of pregnancy, using a malleable metal cannula and ultrasound guidance. Villi were obtained from 47 patients (84%), with sampling success rising to 93% after experience. Immediate complications were noted in 14% of patients and correlated with placental positions situated furthest from the cervical canal. Karyotyping from cultured and/or direct preparations was attempted on the villus samples and was successful in 42. Clarity of the karyotypes obtained from direct preparations in this series was not found to be adequate for diagnostic purposes. A number of practical suggestions which facilitate chorion villus sampling are described.

Biopsy, Needle↗
PubMed1985

Measurement of autoregulation of retinal blood flow using the blue field entoptic phenomenon.

Autoregulation of retinal blood flow was studied in seven normal volunteers. The stimuli to autoregulation used were hyperoxia and hypoxia under controlled conditions of isocapnia. Macular blood flow was measured using the blue field entoptic phenomenon and retinal artery and vein diameters were measured using a computerised digitising system. Results under conditions of isocapnic hypoxia showed a 38 per cent average increase in blood flow and an increase in diameter of 8.2 per cent and 7.4 per cent in retinal arteries and veins respectively. In hyperoxia blood flow fell by an average of 36 per cent and retinal artery and vein diameter decreased by 5.6 per cent and 10 per cent respectively.

Adult↗
PubMed1980

Computed tomography of the nasopharynx: normal and variants of normal.

In 52 normal nasopharyngeal computed tomographic (CT) scans the various tissue planes deep to the mucosa were always seen and appeared symmetric. The superficial structures were more often asymmetric; however, by using physiologic maneuvers, coronal scanning, and this very reliable deep plane anatomy, a highly accurate interpretation is possible. A knowledge of these simple scanning techniques and of the range of normal anatomy will help radiologists avoid the equivocal and false-positive interpretations that plague other radiographic studies of this area. Because of its deep plane information, CT best complements the clinical evaluation of the nasopharynx, and should be the radiographic examination of choice.

Adenoids↗
PubMed1978

Immunofluorescent localization of Staphylococcos aureus antigen in acute bacterial endocarditis nephritis.

A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed deposition of immunoglobulins and complement in the glomeruli. In addition, bacterial antigenic material was demonstrated in the glomeruli by indirect immunofluorescence. These observations further support the hypothesis of an immune-complex pathogenesis in this form of glomerulonephritis.

Acute Disease↗