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Biomedical subjects

D Mathieu

Publications and source records attributed to D Mathieu.

At least 91 records · Page 5Linked to original sources
PubMed1987

Budd-Chiari syndrome: dynamic CT.

A retrospective multi-institutional study was carried out on a series of 38 patients with histologically proved Budd-Chiari syndrome: Five patients had acute disease, and 33 had subacute or chronic disease. All patients underwent dynamic CT scanning. Angiography was performed in 20 cases, inferior cavography in 22, and wedge-hepatic venography in 16. In all acute cases, CT showed global liver enlargement with diffuse hypodensity on plain scans and patchy enhancement after contrast material injection. Thrombosis of the three main hepatic veins was always demonstrated. In subacute or chronic disease, plain CT scans showed abnormalities of liver morphology and hypodensity either in atrophic areas (19 cases) or in the periphery of the liver (eight cases). With dynamic CT, patchy enhancement was present in 28 cases. Correlation with angiography in 15 cases revealed a normal portal blood flow in enhanced areas and an inversed portal blood flow in atrophic areas. Different morphologic and enhancement patterns on CT scans could be related to the direction of portal blood flow, which changes with different stages of Budd-Chiari syndrome.

Acute Disease↗
PubMed1987

[Effects of vaccination in urinary infections caused by Escherichia coli in rats].

The preventive effects of the immunomodulator P40 on the experimental E. coli infection of the lower urinary tract of the rat have been reported previously. In the present paper are presented the results obtained with the aid of vaccination using the same experimental model of infection in the rat. Active specific immunization of the animals with a vaccine consisting of the same strain as that used for infecting the rats afforded significant protection toward the infection. It is concluded that such vaccines could also be used in humans, either alone or in combination with other therapies with the aim at preventing recurrencies or relapses of infections of the lower urinary tract which were resistant to antibiotherapy.

Animals↗
PubMed1986

Hepatic adenomas and focal nodular hyperplasia: dynamic CT study.

A retrospective, multi-institutional study was carried out on a series of 50 histologically proved benign hepatic tumors. The 27 hepatic adenomas (HAs) and 23 cases of focal nodular hyperplasia (FNH) were studied with ultrasonography (US) and dynamic computed tomography (CT). Angiography was performed in 26 cases (15 HAs, 11 FNHs); scintigraphy was not used because of its cost. US scans proved nonspecific. CT scans demonstrated hemorrhage in five HAs and were useful in characterizing tumoral vascularity and any intratumoral features such as necrosis or central fibrous scar. The presence of arterial vessels (five patients) in the projection of this central fibrous scar is suggestive of FNH. Dynamic CT scans did not show the type of tumor in most cases. In cases with lesions greater than 3 cm for which doubt as to the diagnosis persists, combined use of morphologic data, scintigraphy, dynamic CT scanning, and angiography can guide the therapeutic decision: surgery or follow-up CT study after use of oral contraceptives is stopped.

Adenoma↗
PubMed1986

Periportal tuberculous adenitis: CT features.

The computed tomographic (CT) findings in six patients with periportal tuberculous adenitis were reviewed retrospectively to analyze the main morphologic features of the disease. In all patients, hypodense lymph nodes were observed close to the porta hepatis, with peripheral enhancement seen after administration of contrast material. In one patient, this hypodense adenopathy was associated with homogeneous, normally enhancing lymph nodes. These different features on the CT scans could signify the evolving pathologic stages of the disease, with early noncaseating granulomas and subsequent caseation necrosis. Recognition of these hypodense lymph nodes, especially in patients at risk, should help optimize the correct diagnosis of periportal tuberculous adenitis.

Adult↗
PubMed1986

[Comparative study of the results of the detection of bacteriuria using the AUTOBAC apparatus and the classical method].

The comparative study of the results of detection of bacteriuria in 214 samples did not show an evidence of major discrepancies between the classical reference technique on solid media and the AUTOBAC technique on liquid media. The AUTOBAC provides a reliable and rapid test for bacteriuria which saves time and material for the laboratory. Although it has raised considerable interest, it should be used with caution in aplasic or immunodeficient patients in whom the classical criteria of urinary infection cannot be rigourously applied.

Bacteriological Techniques↗
PubMed1986

CT features of cardio-pericardial masses.

The results of dynamic computed tomography (CT) in 13 patients with intracardiac filling defects and one with a pericardial lipoma are presented. The intracardiac filling defects were due to thrombus in five cases, myxoma in three, hydatid cysts in three, haemangiopericytoma in one and sarcoma in one. These kinds of lesions are well identified by CT which seems to be superior to echocardiography in the characterisation of the components and in the evaluation of the malignant spreading masses.

Adult↗