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D Marks

Publications and source records attributed to D Marks.

13 recordsLinked to original sources
PubMed1991

Social judgements of sex and blame in the context of AIDS: gender and linguistic frame.

A questionnaire study (N = 318) examined social judgements of sexually active males and females on positive and negative evaluative dimensions, as a function of the perceiver's gender, and the linguistic frame of judgement. This frame was manipulated by requiring respondents to rate themselves on a number of descriptive dimensions which evaluatively favoured either a 'liberal' or a 'conservative' approach to sex and personal relationships, before making their judgements. Female targets were rated more negatively than males on both evaluative dimensions. There were also significant interactions between the framing manipulation and both subject and target gender for the evaluatively positive measure. There was some evidence of females being perceived more positively in the liberal than the conservative frame and within the conservative frame they were judged less positively than male targets. Male subjects tended to rate targets more positively in the liberal frame whereas females did not. Judgements of blame and personal responsibility in the context of AIDS were examined as a function of the independent variables and also revealed gender differences. These factors, and particularly the importance of language in framing the context of self-perception and social judgement, are discussed.

Acquired Immunodeficiency Syndrome↗
PubMed1990

Artificial insemination with donor semen: the necessity of frequent donor screening.

Artificial insemination with donor semen has become a well established alternative for couples with untreatable male factor infertility. Because of the widespread use of donor insemination, and the increasing awareness and prevalence of sexually transmitted diseases, the American Fertility Society recently redrafted procedural guidelines for the use of donor screening for insemination. Our series of donor screenings is reported to emphasize the necessity of donor evaluations at frequent intervals. From June 1986 through August 1987, 48 healthy male volunteers presented as potential semen donors for our donor program. Each was evaluated with a careful medical history, physical examination and 2 semen analyses for evidence of sexually transmitted disease. On initial evaluation, no donor presented with a positive human immunodeficiency virus antibody, abnormal karyotype, elevated serum glutamic oxaloacetic transaminase, rapid plasma reagent, or positive cultures for Chlamydia or Mycoplasma. One potential donor was excluded because of a positive hepatitis B-core antibody and 1 because of a positive IgM test for cytomegalovirus. At initial examination 3 potential donors had a positive culture for Ureaplasma; all 3 were treated with 3 weeks of tetracycline, and repeat cultures were all negative. Routine followup screening was performed on all donors at 3-month intervals for all sexually transmitted diseases. During this 14-month period cultures converted to positive for Ureaplasma in 4 donors. Furthermore, 1 donor at 6 months contracted gonorrhea. He was treated but no longer used as a donor. Since initiation of the outlined protocol more than 800 inseminations have been performed using fresh semen with no case of sexually transmitted diseases reported from our recipients. We conclude that careful sexual history, and frequent donor and semen evaluation are necessary for prevention of diseases that might be transmitted sexually. If these precautions are strictly observed use of donor semen is safe and effective.

Acquired Immunodeficiency Syndrome↗
PubMed1988

Therapy of primary diffuse large cell lymphoma of the penis with preservation of function.

Only 7 cases of primary lymphoma of the penis have been described previously. We report a case of diffuse large cell lymphoma of the glans penis. The clinical features, histology and management of these cases are reviewed. The previously reported cases were treated with surgical resection or radiotherapy resulting in some degree of local morbidity. Our patient achieved complete remission after only 1 cycle of chemotherapy. The benefits of chemotherapy over surgery or radiotherapy for primary lymphoma of the penis are discussed.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

Anatomic correlates of interhippocampal seizure propagation time.

The relation between interhippocampal seizure propagation time (IHSPT) and anatomic alterations in the human epileptic hippocampus may provide insight into the pathophysiology of temporal lobe epilepsy (TLE). Using depth electrode recordings, we measured the time required for spontaneous seizures with onset in one hippocampus to become manifest in the contralateral hippocampus in 50 patients who underwent resection of the temporal lobe of seizure origin. Cell densities in individual hippocampal subfields were determined and correlated with mean IHSPT for each patient. Mean IHSPT was significantly and inversely correlated with cell counts in CA4 only (r = -0.38, p less than 0.01, Pearson's product correlation; r = -0.52, p less than 0.001, Spearman's rank order correlation). In 5 patients with bilateral independent hippocampal seizure onset who had temporal lobectomy and a diagnosis of mesial temporal sclerosis, mean IHSPT was consistently longer from the sclerotic temporal lobe than to it. These observations suggest that anatomic changes associated with chronic epilepsy alter propagation patterns. Because CA4 is believed to modulate the output of dentate granule cells and also has commissural connections to the contralateral homotopic area, the association of decreased CA4 cells with prolongation of IHSPT suggests that the observed anatomic alterations may actively (through increased inhibition) or passively (through decreased recruitment) interfere with various routes of seizure propagation.

Cell Count↗
PubMedDate not supplied

Nursing observations of central venous catheters. The effect on patient outcome.

The purpose of this descriptive study was to obtain information concerning rates of intravascular infection in patients with central lines and to identify the variables related to nursing care of these lines that may influence the development of systemic infection. The study was conducted at a large southern teaching hospital during a 6-week period. The sample for this study consisted of adult inpatients who underwent central-line insertions. The results suggested that careful nursing observations, combined with early recognition and intervention, can significantly influence a positive patient outcome.

Adult↗