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Biomedical subjects

D Maquin

Publications and source records attributed to D Maquin.

6 recordsLinked to original sources
PubMed2005

Linear mass balance equilibration: a new approach for an old problem.

Interval analyses are well known in the mathematics literature but have found few applications in control engineering. Based on the interval concept, we present here a methodology for data reconciliation and mass balance equilibration which is a very classical problem in mineral and chemical engineering. Indeed, this problem is solved with the view of inequality constraints which allows us to represent measurements by interval without particular knowledge and hypothesis about the density probability function of the measurement errors. As a main result, the paper gives a set of solutions for the reconciled data under an interval form and not only one solution as is the case with classical approaches.

Algorithms↗
PubMed2000

Data reconciliation with uncertain models

Data reconciliation has proven to be an effective technique for providing frequent, accurate and consistent "best estimates" of plant operation data. However, in almost all the proposed techniques until today, the mathematical model of the process has been considered as exact. In point of fact, this hypothesis is uncommon and frequently the models used are uncertain. This paper proposes a new technique of data reconciliation which is able to exploit the knowledge about the uncertainties of the model with regard to which the reconciliation is done. It leads to the solution of a classical quadratic optimisation problem subject to constraints. The originality of the proposed technique is to use penalty functions for solving this problem and to weight each constraint with regard to their uncertainties.

Journal Article↗
PubMedDate not supplied

Biological characterization of experimental carbon samples.

The use of carbon is widespread in fields as wide as aeronautics, cars, electricity or electronics. The biomedical applications of carbon are also numerous. The purpose of our work is to test four experimental carbon fibers (A, B, C and D; B being the negative control) to determine the best clinical application. Four tests of cytocompatibility are carried out (cell viability, inflammatory test, cell proliferation and cell morphology). Two different cell lines are used: the L132 cell line (epithelial embryonic pulmonary human cell) and the HaCaT line (human normal spontaneously immortalized skin keratinocytes). The results of the biological tests are compared with those of a carbon fiber sample already marketed as a bandage in the treatment of infected wounds: Actisorb "Plus (J2). The various tests show us that only two experimental samples are slightly cytotoxic (A, D). On the other hand, no sample supports cell adherence. A, B, C and D do not have an inflammatory effect. J2 appears at the same time cytotoxic and inflammatory. Consequently, being given the physical presentation and the biological properties of experimental samples (A, C and D), we intend them for an application in the field of wound healing, as a bandage. Also further experimentation is needed.

Biocompatible Materials↗