Biomedical subjects
Publications and source records attributed to D M Wexler.
Rollerblading is increasingly popular in the UK. Over 12 weeks, we treated 29 patients of whom 34 per cent required operative intervention. There was a wide range of injuries, those of the radius being most common, and some (e.g. femoral and pelvic fractures) being quite severe. The value of protective equipment is discussed.
A case of transient generalized arthralgia in a young female patient following the intravenous administration of Gd-DTPA (dimeglumine gadopentetate-Schering) is presented. We believe that this is the first report of an adverse drug reaction of this nature.
Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's disease, and collagen vascular disorders. Since cyclosporin A has a potentially important use in dermatology, and since a number of dermatologic side effects are seen as a consequence of its use, it is important that dermatologists be familiar with this drug.
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