Biomedical subjects

D M Mitchell

Publications and source records attributed to D M Mitchell.

At least 145 records · Page 8Linked to original sources

PubMed1977

Knee joint bursal abnormalities in rheumatoid arthritis.

Twenty-five patients with rheumatoid arthritis presented with knee joint bursal abnormalities. Nineteen patients presented with symptoms simulating thrombophlebitis. Sixteen had a rupture of the posterior joint capsule without a communicating semimembranosus-gastrocnemius bursa (S-G), with extension ventrally between the soleus and gastrocnemius muscles or between the skin and muscle. Nine had an enlarged S-G bursa with or without rupture. Two patients had additional cephalad ruptures: one from the posterior compartment and the other one from the suprapatellar bursa.

Arthritis, Rheumatoid↗

PubMed1976

Joint pain or arthritis.

Explore the source record for details and available documents.

Arthritis↗

PubMed1976

Ultrastructural changes produced in rheumatoid synovial membrane by chrysotherapy.

Biopsies of rheumatoid synovial membrane before and after chrysotherapy were examined with the light and electron microscopes, and subjected to electronprobe x-ray analysis. The main change noted was the occurrence of electron-dense deposits of characteristic morphology within pre-existing lysosomes. Such deposits were also seen in other varieties of lysosomal bodies. X-ray analysis showed the presence of gold, phosphorus, osmium, and calcium in these deposits. The present study shows that gold enters the pre-existing lysosomes, supporting the concept that the beneficial effects of chrysotherapy are due to its action on the lysosome.

Adolescent↗

PubMed1976

Nuclear fibrous lamina in the rheumatoid synovium.

Biopsy specimens of synovial membrane were obtained from patients with rheumatoid arthritis and from patients with nonrheumatoid conditions. Comparison of the mean thickness of the lamina in the rheumatoid and nonrheumatoid groups showed a statistically significant thickening of the lamina in the rheumatoid group (rho less than .01). There was no statistically significant difference in the thickness of the lamina before and after chrysotherapy.

Adolescent↗

PubMed1976

Dermatomyositis following rhabdomyolysis.

A case is presented, in which classic dermatomyositis occurred six weeks after documented rhabdomyolysis. The literature concerning the immunopathogenesis of dermatomyositis is briefly reviewed.

Adult↗

PubMed1974