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Biomedical subjects

D M Hynes

Publications and source records attributed to D M Hynes.

9 recordsLinked to original sources

Evaluating productivity in clinical research programs: the National Cancer Institute's (NCI) Community Clinical Oncology Program (CCOP).

This paper outlines an approach to studying productivity in clinical research programs that incorporates environmental, organizational, provider, and patient specific factors in the model of production process. We describe how this approach has been applied to the National Cancer Institute's (NCI) Community Clinical Oncology Programs (CCOPs). Next, a practical evaluative model of the productive process in CCOPs is outlined and its use in evaluation and monitoring performance in CCOPs is discussed. Each level of the model is described and a number of factors potentially affecting each level are explored. Finally, we discuss the strengths and weaknesses of this approach and show how management can use it to study and improve the productivity of clinical research programs.

Catchment Area, Health

Digital videofluorography: a new direction in diagnostic imaging.

Accurate information about digital technology is often difficult to obtain because of unrealistic expectations. The development of the digital department is complex and must not be understated. However, we have attempted to show that if a truly committed hospital immediately accepts DVF, this will result in reduced capital and operational costs, as well as lower radiation doses to the patient and operator. We believe this will happen because every major X-ray manufacturer is demonstrating and offering DVF systems, all of which are based on the technology described in this paper. These systems can either be totally integrated into fluoroscopic facilities or be purchased as add-on components to established units. In any event, a modern fluoroscopic facility can cost several hundred thousand dollars, and must last 10 to 15 years. It seems prudent to acquire quality and digital capability so that these units will be adequate in the year 2000 and beyond.

Attitude of Health Personnel

Clinical comparison of analog and digital 100 mm photofluorography.

Many of the problems associated with digital acquisition of clinical images from x-ray intensifier/television systems have been eliminated by the use of a pulsed progressive readout from a 1024 line television camera into a 1024 x 1024 pixel image store, the whole arrangement triggered by the circuitry of a 100 mm camera. By means of a beam splitter, this study demonstrates a clinical comparability between 100 mm and digital images under identical conditions. In addition, radiation dose levels can be reduced by tailoring exposures to individual patients and their clinical needs. Several clinical cases are presented to illustrate the interchangeability of the new digital modality for fluoroscopic examination with an ordinary sized x-ray image intensifier.

Bone and Bones

Radiographic, photofluorographic, and television imaging systems: an evaluation.

A feasibility study for the photographic recording of fluoroscopic images from a high resolution system is described. Resolution on the television monitor was 2 line pairs/mm, making clinically acceptable recordings possible. Significant reductions in radiation dose to the patient and potential financial savings are indicated if a multiformat camera is developed to photograph the monitor.

Fluoroscopy

Flow-chart for sequential cholecystography.

A protocol designed to integrate oral cholecystography with ultrasonography and scintiscanning of the gallbladder is presented. The planned use of these modalities will permit a 95% clinically useful assessment on a single visit to the x-ray department.

Cholecystography

Intra-abdominal sepsis--ultrasound evaluation.

The advent of grey-scale ultrasound has made this facility an irreplaceable tool for diagnostic imaging techniques. Although well established in obstetric management, its application to abdominal "body" scanning is not yet fully realized and accepted. These case presentations demonstrate the role of ultrasound in the diagnosis, localization and clinical management of patients with intra-abdominal sepsis. It is emphasized that ultrasound should be used early in the work-up of such problems and is rapidly becoming the investigation of choice. The diagnostic information provided facilitates management, reduces the need for complex investigations and occasionally makes surgery unnecessary.

Abdomen

System for digital acquisition of gastrointestinal images.

Previous theoretical work and clinical experience with digital acquisition of fluoroscopic images have identified several problems which needed to be solved. These are: image resolution; blurring due to patient motion, combined with long exposure times; and excessive x-ray quantum mottle levels. We will show that application of pulsed progressive readout (PPR) methods to the TV camera solves these problems. By permitting a high-intensity x-ray pulse to be delivered, all motion is stopped and quantum mottle is reduced to acceptable levels. It will be shown that 1024 x 1024 digital matrices provide adequate resolution and 8-bit digitization is sufficient to permit the same quality as is used in conventional 100-mm photofluorography. User acceptance can be made easier by incorporation of existing photofluorographic controls (with which the radiologist is already familiar) to acquire the digital images. It is possible to interface PPR video systems using existing 100-mm exposure circuits without much modification and the resulting system can be regarded as a digital 100-mm camera.

Digestive System