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Biomedical subjects

D M Hunter

Publications and source records attributed to D M Hunter.

36 records · Page 2Linked to original sources

Fluorescein angiography and light microscopy studies of retinas irradiated by oxygen nuclei.

Fluorescein angiography and light microscopy techniques were utilized in the rhesus monkey to evaluate retinal damage following oxygen ion irradiation. Particle flux ranged from 1.3 x 10(7) particles/cm2 to 1.5 x 10(8) particles/cm2. Earliest evidence of damage was detected with fluorescein angiograms 24 h after exposures to 7.7 x 10(7) particles/cm2. No evidence of the hypothesized microlesion was found by either technique.

Angiography↗

Heavy-ion-induced cataractogenesis.

Cataract formation following heavy ion exposure (O+8) was noted in three rhesus monkeys secondary to a study of retinal effects. The pathogenesis of these lens changes follows many, but not all, of the characteristics for "radiation cataracts." The ring-shaped opacity was not noted to occur. Posterior capsular changes were noted initially and followed through the formation of a mature cataract.

Animals↗

Retinal change induced in the primate (Macaca mulatta) by oxygen nuclei radiation.

Retinas of primates (Macaca mulatta) were exposed to oxygen nuclei at the Bevatron, Berkeley, California. Color fundus photographs and fluorescein angiograms were taken of the retinas prior to irradiation and up to 5 weeks post exposure. Animals were sacrificed at post exposure intervals for histopathologic examination of the retinas. A series of animals were exposed to 200 kVp X-ray and examined on the same regime as the first series. The results showed a low rad equivalent dose for retinal damage as compared with the X-ray series, i.e., a high quality factor, and a marked compression of the latency between exposure and onset of the retinal pathology.

Animals↗

X-ray imaging using amorphous selenium: a photoinduced discharge readout method for digital mammography.

A new digital image readout method for electrostatic charge images on photoconductive plates is described. The method can be used to read out images on selenium plates similar to those used in xeromammography. The readout method, called the air-gap photoinduced discharge method (PID), discharges the latent image pixel by pixel and measures the charge. The PID readout method, like electrometer methods, is linear. However, the PID method permits much better resolution than scanning electrometers while maintaining quantum limited performance at high radiation exposure levels. Thus the air-gap PID method appears to be uniquely superior for high-resolution digital imaging tasks such as mammography.

Female↗

Ankle flexibility and injury patterns in dancers.

Lower-extremity injuries are common among dancers and cause significant absences from rehearsals and performances. For this study of lower-extremity injuries in 101 ballet and 47 modern dance students, injuries requiring medical attention sustained over 1 academic year were associated with the following data obtained at the beginning of the school year: ankle flexibility, sex, dance discipline, previous injury, body mass index, and years of training. Eighty-three of the 148 students (age range, 12 to 28 years) reported prior lower-limb injuries, the most common being ankle sprains (28% of all dancers). Previous leg injuries correlated significantly with lower dorsiflexion measurements and with more new injuries. Female students had greater ankle and first metatarsophalangeal flexibility. Modern dancers had greater ankle inversion. Ninety-four students sustained 177 injuries during the study, including 75 sprains or strains and 71 cases of tendinitis. Thirty-nine percent (N = 69) were ankle injuries; 18% (N = 33) were knee injuries; 23% (N = 40) were foot injuries; and 20% (N = 35) were either hip or thigh injuries. Sixty-seven percent (N = 78) of the injured students were ballet dancers. Age, years of training, body mass index, sex, and ankle range of motion measurement had no predictive value for injury; previous injury and dance discipline both correlated with increased risk of injury.

Adolescent↗