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Biomedical subjects

D M Hays

Publications and source records attributed to D M Hays.

124 records · Page 7Linked to original sources
PubMed1966

The changing face of intussusception.

Management of intussusception in a pediatric center shows changing patterns over the past 26 years. Early and subacute cases of intussusception are now ordinarily successfully reduced by hydrostatic pressure (barium enema). A minority, who are in shock, who have evidence of significant blood loss or, in whom small intestinal obstruction is apparent, are treated by emergency laparotomy, with or without confirmatory contrast studies. In the latter group the rate of resection is high (16.4% in the present series). Resected segments are microscopically infarcted; with unnecessary resection a rarity. Advances in surgical management have eliminated a major portion of the mortality formerly associated with resection. The use of hydrostatic pressure reduction makes surgery unnecessary in a high percentage of infants with intussusception, but does not reduce the incidence of infarction requiring resection. Ambulatory or nonhospital management of intussusception subjects the infant to the risk of a significant delay in definitive treatment and is not to be condoned.

Humans↗
PubMedDate not supplied

Bladder/prostate rhabdomyosarcoma: results of the multi-institutional trials of the Intergroup Rhabdomyosarcoma Study.

Rhabdomyosarcomas (RMS) occurring in pelvic sites are almost entirely of the embryonal histologic subtype and are relatively responsive to chemotherapeutic agents. When treated by radical surgery, pelvic irradiation, and intensive chemotherapy for 2 years, survival rates of higher than 85% have been achieved. However, the effects of such therapeutic approaches have resulted in major changes in the quality of life of survivors, because of the loss of pelvic organs, primarily the bladder. Current efforts are directed towards achieving long range survival with procedures that are less extensive than pelvic exenteration or total cystectomy and by regimens that eliminate or reduce the intensity of radiotherapy. Until the past 5 years, these efforts have been relatively unsuccessful in both North America and Europe. However, the most recent studies of the IRS and European cooperative groups suggest that a majority of these patients can survive with intact pelvic organs when treated with currently available chemotherapeutic agents in conjunction with radiotherapy and limited surgery.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

Calorie and protein requirements of pediatric patients with acute nonlymphocytic leukemia.

The calorie and protein requirements wer studied in 6 pediatric patients with acute nonlymphocytic leukemia treated in a laminar air flow unit. Calorie and protein requirements were estimated from anthropometric data. Mean total caloric requirement for weight maintenance was 136% of estimated basal metabolic rate, which is much lower than the RDA for healthy children. The mean protein requirement was 108% RDA. Provision of intravenous nutrients depressed oral intake. Infection had a deleterious effect on visceral protein status as determined by serum albumin.

Acute Disease↗
PubMedDate not supplied

Use of Hickman right atrial catheter in pediatric oncology patients.

Eighteen pediatric oncology inpatients had 21 Hickman right atrial catheters placed for total venous access; 16 patients received parenteral nutrition. Mean duration of catheterization was 43 +/- 29 (SD) days. Four catheters had to be removed for infection or clotting. The catheter-related sepsis rate was 10%. Serious catheter-related complications were no more frequent in this population than in patients receiving only parenteral nutrition via Broviac or pediatric Broviac catheters.

Adolescent↗