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Biomedical subjects

D M Gallant

Publications and source records attributed to D M Gallant.

At least 37 records · Page 2Linked to original sources

Patterns of substance use on a college campus: a 14-year comparison study.

In 1972, a drug incidence survey was conducted at a private southern university. Pooled results of this random survey of 1,032 students revealed that on at least one occasion, 90% of the students had tried alcohol, 70% had used tobacco, and 61% had experimented with marijuana. Use of amphetamines (38%), hallucinogens (28%), barbiturates (19%), and cocaine (10%) was much lower. To evaluate the apparent change in trends of drug usage, a follow-up study was undertaken in 1986 at the same school. The results showed a decline in amphetamine and barbiturate use. The greatest differences were seen in the nearly fourfold increase in one-time use of cocaine between 1972 and 1986 and the sixteenfold increase in students who used cocaine more than 10 times. It was noteworthy that one-third of the students who used marijuana had done so by the 9th grade. Similar early experimentation was noted with a majority of the other drugs.

Adult↗

Antidepressant overdose: symptoms and treatment.

In recent years, an increased use of antidepressant medications has resulted in a heightened incidence of drug overdose. Because of this increased use, more types of antidepressant agents have become available. Therefore, emergency-room physicians not only have to recognize the overdose patient (often unwilling or unable to communicate with the physician), but also, identify the overdose agents if possible, and initiate early and appropriate treatment. Recognizing overdose signs and symptoms associated with various antidepressant agents is essential in choosing the appropriate treatment. Tricyclic agent overdoses account for most of the hospital admissions and deaths due to antidepressant therapy; a majority of these deaths are attributable to cardiac complications. In contrast, trazodone, one of the safest drugs when taken in overdose, is not associated with cardiac arrhythmias. Thus, trazodone-overdose patients generally require only emesis and/or gastric lavage, and minimal supportive therapy, whereas tricyclic antidepressant overdoses often require more aggressive intervention.

Antidepressive Agents↗

Outpatient treatment: community and private practice support systems.

Support systems and psychosocial techniques in the outpatient care of schizophrenia are discussed. Such approaches as social skills training, behavior modification, major role therapy, and family management can be used in both the public and private sectors to foster treatment adherence and increase patients' ability to function in the community. Steps in establishing an effective aftercare program are outlined, and it is suggested that the development of community coordination centers can enhance efforts to reduce rehospitalization and improve vocational and social functioning.

Aftercare↗

An evaluation of a unique new antipsychotic agent, sulpiride: effects on serum prolactin and growth hormone levels.

Sulpiride is a new and chemically different neuroleptic. In a study of 16 severely ill schizophrenic patients, this compound displayed definite evidence of antipsychotic activity while producing few adverse reactions. The relative absence of extrapyramidal side effects may indicate that sulpride has a low potential for producing tardive dyskinesia. Two patients who did not develop significant increases in prolactin levels did show a definite therapeutic response to sulpiride. Thus it appears that central dopaminergic blockade in the hypothalamic area is not a prerequisite for antipsychotic activity.

Adult↗