Search PubMed⌕ Search

Biomedical subjects

D M Fraser

Publications and source records attributed to D M Fraser.

67 records · Page 4Linked to original sources
PubMed1976

Peripheral and autonomic nerve function in diabetic ketoacidosis.

Peripheral and autonomic nerve function was assessed at intervals over a 3-month period in seven diabetics after ketoacidosis. There was marked improvement in motor conduction velocity and terminal latency of both ulnar and common peroneal nerves in all patients. Five had one or more abnormal autonomic function tests but there were no consistent changes during the same period. It is postulated that peripheral nerves may be more susceptible to acute metabolic damage than autonomic fibres.

Adolescent↗
PubMed1976

Mononeuritis multiplex in a patient with macroglobulinaemia.

A case is described of a 73 year old male with Waldenström's macroglobulinaemia and hyperviscosity in association with neurological abnormalities, the Bing-Neel syndrome. The relationship of the clinical features to changes in serum viscosity and the response to therapy with plasmapheresis and chlorambucil are discussed.

Aged↗
PubMedDate not supplied

Small muscle wasting of the hands in diabetes mellitus.

The clinical features and peripheral somatic and autonomic nerve function were studied in 10 diabetic subjects (nine men, one woman; mean age 59 yr, range 41-68 yr; mean duration of diabetes 20 yr, range 8 mo to 33 yr) with generalized small muscle wasting of the hands. Five patients were insulin-dependent and five non-insulin-dependent. Nine had retinopathy (two proliferative, seven background), five nephropathy, two ischemic heart disease, and seven peripheral vascular disease. Nine patients had clinical evidence of sensory peripheral neuropathy and absent reflexes in the lower limbs. Eight patients had distal sensory impairment and/or absent reflexes in the upper limbs. Seven had two or more symptoms of autonomic neuropathy. Nerve conduction measurements in the median, ulnar, and lateral popliteal nerves showed that all patients had moderate to severe polyneuropathy affecting both motor and sensory fibers. Nine had one or more abnormal cardiovascular autonomic function tests. Electromyography of affected muscles in the hands showed changes of chronic partial denervation and collateral reinnervation in all cases.

Adult↗