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Biomedical subjects

D M Davies

Publications and source records attributed to D M Davies.

At least 37 records · Page 2Linked to original sources
PubMed1989

Morphological and morphometric changes in revascularised bowel grafts reconstructing the cervical oesophagus.

Revascularised grafts of jejunum and colon have been used to reconstruct the cervical oesophagus in dogs. The grafts were examined at 2 months to assess their morphological and morphometric behaviour in their new position in the oesophagus. The colonic grafts appeared to adapt completely, while the jejunal ones manifest persisting mucosal changes attributable to their new environment.

Animals↗
PubMed1988

Interaction of cytochrome b5 with surfactant vesicles.

Changes in the u.v.-visible absorption spectrum of cytochrome b5 which occur upon addition of dicetyl phosphate, dimyristoyl phosphatidic acid (DMPA), or mixed DMPA/dimyristoyl phosphatidylcholine vesicles are consistent with haem transfer from the cytochrome to the membrane via an intermediate haemoprotein species. The effects of vesicle charge and concentration on the kinetics of haem transfer are discussed.

Animals↗
PubMed1988

Doppler waveforms in the fetal aorta and umbilical artery in patients with hypertension in pregnancy.

Pulsed Doppler ultrasound assessment of blood flow was performed in the fetal aorta and umbilical arteries of 41 patients with hypertension in pregnancy. Patients were grouped according to severity of the hypertension and the presence or absence of chronic hypertension. Doppler abnormalities were seen in two patients with chronic hypertension, both of whom delivered small for gestational age infants. Only one patient with mild to moderate preeclampsia had abnormal aortic Doppler assessment and was also delivered of a small for gestational age infant. The highest number of abnormal Doppler waveforms in both fetal aorta and umbilical artery were found in patients with severe preeclampsia. Abnormalities were detected more frequently in the fetal aorta than in the umbilical artery. Doppler assessment was often abnormal before a nonstress test or biophysical profile. The number of abnormal Doppler values correlated with perinatal outcome in patients with severe preeclampsia.

Adult↗
PubMed1988

Phalloplasty using the free radial forearm flap.

Our experience of phalloplasty using the radial forearm flap in five transsexual cases is reported. The results are disappointing due to the high incidence of complications. We had partial success in two cases, both complicated by a fistula, and complete failure in three cases due to vascular thrombosis.

Female↗
PubMed1988

A method of phalloplasty using the deep inferior epigastric flap.

Penile reconstruction remains a difficult surgical problem. To produce a phallus capable of erection and with a water-tight urethra to the tip has not been solved satisfactorily even by the introduction of free flap transfers. We present a method used in four cases, three transsexuals and one pseudohermaphrodite, in which a phallus was successfully constructed using the deep inferior epigastric flap.

Abdominal Muscles↗
PubMed1988

The innervated trapezius flap in facial paralysis.

The use of an innervated lateral trapezius flap to allow movement of the paralysed face is described. Five cases are presented, all of whom achieved some facial movement postoperatively. The place of this technique in the armamentarium of procedures for facial reanimation is discussed.

Accessory Nerve↗
PubMed1988

The functional recovery of revascularised colon and jejunum replacing the cervical oesophagus.

An experimental animal model was set up to study the comparative behaviour of revascularised transplants of colon and jejunum used to reconstruct the cervical oesophagus. Age, sex and size matched greyhound dogs were used in the study. An investigation of the physiological behaviour of the graft mucosa was carried out at 8 weeks using the mucosal specific activity of the enzyme Na+K+ATPase. The findings demonstrate a clear depression in the functional behaviour of the jejunal graft mucosa, while the colonic graft mucosa remained biochemically unchanged. The significance of these findings is discussed, and the conclusion drawn that they support the hypothesis that colon makes a more stable and functionally superior free graft than jejunum when replacement of the cervical oesophagus is required.

Animals↗
PubMed1987

Experimental assessment of free jejunal and colonic grafts of the esophagus.

The reconstruction of the cervical esophagus and the hypopharynx by revascularized bowel grafts has become a well-recognized treatment option and often is the method of first choice. Problems described by several protagonists of the standard revascularized jejunal graft have caused us to hypothesize that the colon provides both a suitable alternative and a solution to these problems. Experimental work in dogs demonstrates clear functional differences between colon and jejunum as free esophageal grafts. Video-fluoroscopic and manometric assessment of the two types of graft show that structurally and functionally the colon integrates into the new position in the esophagus better than does the jejunum.

Animals↗
PubMed1987

Jejunum versus colon for free oesophageal reconstruction: an experimental radiological assessment.

The reconstruction of the cervical oesophagus and the hypopharynx by revascularised bowel grafts has become a frequently described treatment option. Problems with the standard jejunal grafts have led us to suggest that the colon provides a suitable alternative. Experimental work in dogs demonstrates clear functional differences between colon and jejunum as free oesophageal grafts, and shows how structurally and functionally the colon integrates into the new position in the oesophagus better than the jejunum.

Animals↗
PubMed1986

Complications of radial forearm flap donor sites.

The complications of radial forearm flap donor sites in 15 patients from two centres have been reviewed. The complications included skin graft failure, swelling of the hand, stiffness of joints, reduced strength and sensation, cold-induced symptoms and fractures of the radius. Methods to reduce the incidence of such complications are discussed.

Adult↗
PubMed1986

The anatomy of the thoracodorsal artery within the latissimus dorsi muscle.

This paper reports the findings of an anatomical study of the primary and secondary muscular branches of the thoracodorsal artery within the latissimus dorsi muscle. Twenty latissimus dorsi muscles were studied, harvested from 13 fresh cadavers and the findings support the hypothesis that it is possible to thin safely a latissimus dorsi muscle flap at the time of flap transfer.

Arteries↗
PubMed1986

Injury to the upper cervical spine: fracture versus congenital anomaly.

As skull and cervical spinal radiographs are being obtained routinely on head and neck injuries, more incidental anomalies of the neck region are being detected. The differentiation of congenital anomaly from fracture can be difficult. The importance of this, however, cannot be underestimated because of the dire consequences of a missed cervical fracture. A case of such an anomaly and its presentation following injury is presented.

Adolescent↗