The purpose of this study was to measure concentrations of adrenaline (A), noradrenaline (NE), free tryptophan (f-Trp), prolactin (PRL), nonesterified fatty acids (NEFA), and blood lactate following 30 s of high-intensity cycle ergometer exercise. Adrenaline (A) and NE concentrations increased immediately postexercise (P < 0.05) and returned to levels observed at baseline 24 h later. Plasma f-Trp concentration decreased by 23.5% immediately following exercise (P < 0.05). There were no changes observed in serum concentrations of PRL. Plasma NEFA concentrations decreased immediately following exercise by 46% (P < 0.05) and returned to baseline values 24 h later. Whole blood lactate concentrations increased immediately post exercise (P < 0.05), and were higher than those measured 24 h later (P < 0.05). These findings indicate that blood markers of serotoninergic activity were unaltered by a single 30 s bout of maximal cycling.

Adult↗

PubMedDate not supplied

First year of AIDS services delivery under Title I of the Ryan White CARE Act.

This is a review of (a) the emergency assistance for ambulatory HIV medical and support services provided in the first year by eligible metropolitan areas (EMAs) funded under Title I of the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act of 1990, (b) the varied responses and processes by which the 16 urban areas receiving Title I funds in 1991 met legislative mandates, (c) the central nature of planning councils under Title I and their formation and functioning, and (d) issues related to current implementation and future expansion of Title I to additional eligible metropolitan areas. Integral to the review is a brief discussion of the history of AIDS and HIV infection, particularly in cities receiving CARE Act funding, an overview of Title I requirements, and a description of the organizational structures cities are using to implement Title I. Information on Title I EMAs is based on analysis of their 1991 applications, bylaws of their HIV service planning councils, intergovernmental agreements between Title I cities and other political entities, and contracts executed by Title I grantees with providers for the delivery of services. Interviews with personnel in several Title I EMAs, including planning council members and grantee staff members, provided additional information. This is the first descriptive accounting of activities related to the 1991 applications for and uses of Title I funds, and the administrative and service issues related to this process.

Acquired Immunodeficiency Syndrome↗

PubMedDate not supplied

A work program in psychiatry.

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Hospitals, Psychiatric↗

PubMedDate not supplied

Energy contingency planning for health facilities: conference report.

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Conservation of Energy Resources↗

PubMedDate not supplied

Blood lipid and lipoprotein concentrations in active, sedentary, healthy and diseased men.

AIM: To examine differences in resting blood lipid and lipoprotein concentrations in male subjects of varying degrees of cardiovascular fitness ranging from the healthy elite athlete to the sedentary subject either with or without angiographically confirmed evidence of coronary artery disease (CAD). METHODS: Two-hundred-and-eighty-four clinically asymptomatic male subjects were selected from a group of Olympic distance runners (n = 1 7), physical education athletes (n = 44), and industrial executives (n = 223). Each subject received a detailed physical examination and provided a venous blood sample after fasting, which was analysed for lipid and lipoprotein concentrations. Maximum oxygen uptake was determined using on-line computerised respiratory analysis during a functional diagnostic test. The industrial executive group was further divided according to their electrocardiographic (ECG) response to exercise; negative ECG (n = 138), positive (abnormal) ECG but no angiographic evidence of CAD (n = 18) and positive ECG with angiographic evidence of significant CAD (n=67). RESULTS: Lipid-lipoprotein profiles were consistently abnormal in subjects with a positive ECG and documented evidence of CAD, whereas those subjects who tested negative or false-positive were less affected. The lipid-lipoprotein profiles observed between Olympic distance runners and an age-matched group of physically active students were not significantly different despite clear differences in physical activity patterns. CONCLUSIONS: In addition to the abnormal lipid-lipoprotein profile in subjects with CAD, the present data also suggest that while physical activity confers metabolic cardioprotection, a threshold stimulus exists beyond which no further benefits can be gained.

Adult↗