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Biomedical subjects

D Lomanto

Publications and source records attributed to D Lomanto.

42 records · Page 3Linked to original sources
PubMed1986

Immunocytochemical study of a trabecular carcinoma of the skin (Merkel cell tumor). Case report.

The existence of different neuroendocrine markers was investigated by immunocytochemistry in a case of Merkel cells tumor. Neuroplastic cells contain NSE,NF,CK and chromogranin A i.r. On the basis of the results the neuroendocrine nature of this uncommon neoplasm of the skin is confirmed and it is suggested that chromogranin A could represent an additional marker for Merkel cells tumors.

Adenocarcinoma↗
PubMed1982

Sauvagine-like immunoreactivity in the bony fish urophysis and caudal neurosecretory system.

Immunoperoxidase methods were used to reveal Sauvagine-Like immunoreactivity (SVLI) in the urophysis and whole caudal neurosecretory system of fresh water fish Tinca tinca and Salmo gairdneri L. Both Dahlgren cell cytoplasm and axons, which reach the urophysis, were filled with SVLI granules. The urophysis shows: a) in the medullary zone, several SVLI Dahlgren cells and a thick network of SVLI axons; b) in the cortical zone, a series of complicated neurohemal knots where SVLI axonal endings surround and penetrate the capillary and glial cell networks. An individual variability and the possibility of a release of SVLI material into the cerebrospinal fluid were also demonstrated. These observations further suggest that, besides the biological effects, sauvagine and the urophysial substance urotensin I, may also have a similar structure.

Amphibian Proteins↗
PubMedDate not supplied

[Single-stage laparoscopic surgery of cholelithiasis and choledocholithiasis in 268 unselected consecutive patients].

AIMS: The introduction of laparoscopic cholecystectomy (LC) has modified the treatment of gallstones and common bile duct (CBD) stones. Aim of this prospective study was to evaluate the results of single stage laparoscopic management of gallstones and CBD stones. PATIENT AND METHODS: From January 1991 to October 1999, CBD stones were present at intraoperative cholangiography in 268 patients (pts) (169 females, 99 males, mean age 55.6 years, range 12-94 years) out of 2693 undergoing LC (10%) for gallstones. CBD stones were unsuspected in 123 (45.9%) and suspected in 145 (54.1%). RESULTS: CBD exploration was successful in 264 cases (98.5%) (transcystic 164, choledochotomy 100). Four pts were converted to open surgery (1.5%). Retained stones in 15 patients (5.7%), were treated by ERCP/ES (6 pts) and by percutaneous endoscopic/fluoroscopic stone removal (6 pts). Spontaneous stones passage occurred in 2 pts, one patient is waiting for treatment. Major morbidities were hemoperitoneum (4 cases) and cystic duct bile leakage (3 cases). One high risk patient died postoperatively. Recurrent stones were observed in 5 pts (1.9%), at 1, 4, 8, 18, 26 months respectively after T-tube removal, and were treated by ERCP/ES in 4 cases. Spontaneous stone passage occurred in 1 case. CONCLUSIONS: LC and CBD exploration has shown to be safe and feasible with low morbidity and mortality. The rationale of this approach is to solve two problems during the same procedure, limiting the role of endoscopic sphincterotomy to the treatment of residual ductal stones.

Adolescent↗
PubMedDate not supplied

Primary gastric lymphoma: a 15-year review.

BACKGROUND/AIM: Between 1976 and 1991, 25 patients underwent surgical therapy for primary gastric lymphoma. Clinical records were reviewed retrospectively to evaluate prognostic factors and impact of treatment on survival. RESULTS: Diagnostic sensitivity of endoscopic biopsy was 68%, positively of barium contrast studies for tumor was 33%. The overall 5-year survival rate was 67.3% (51.7% "free disease"): it was for stage I E 88.9%, for stages II 1E and II 2E respectively 68.6% and 44.4% and for stage IV 33.4%. Patients with tumors smaller than 5 cm had a 5-year survival rate of 80.8% whereas for patients with larger lesions survival rate was 44% (p < 0.05). Patients with low grade malignancy tumors had a 5-year survival rate of 81.9% versus 37.5% for high grade malignancy tumors (p < 0.03). Chemotherapy as adjuvant therapy was used in 17 cases (68%). 53% of them are "free disease" at minimum 4 years from the operation. CONCLUSIONS: We conclude that, surgical management of primary gastric lymphoma is mandatory but a planned multimodality therapy may produce complete remission and long-term "free disease" survival rate even in patients with relapse.

Adult↗
PubMedDate not supplied

Bouveret's syndrome: case report and review of the literature.

Bouveret's syndrome, or gallstone duodenal pyloric obstruction, almost always presents with abdominal pain or vomiting. It occurs more commonly in females (65%), with a median age of 68.6 years. The diagnosis is made by endoscopy (60%), upper gastrointestinal series (45%) or by direct abdominal x-ray (23%). The syndrome is mainly treated by surgery (93%), but recently, it has also been treated by endoscopy or extracorporeal shock wave lithotripsy. The mortality rate has improved from 33%, as was the case before 1968, to 12% in recent years. Herein we report the case of a 79-year-old female with Bouveret's syndrome.

Aged↗