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Biomedical subjects

D Lindsey

Publications and source records attributed to D Lindsey.

At least 37 records · Page 2Linked to original sources
PubMed1987

Natural course of the human bite wound: incidence of infection and complications in 434 bites and 803 lacerations in the same group of patients.

Human bites and common lacerations are frequent in certain residential groups in institutions for the care of developmentally disabled individuals. We screened the records of such an institution and studied the course and outcome of 434 human bite wounds and 803 lacerations in the same group of clients. Infection developed in 13.4% of the lacerations, and 17.7% of the bite wounds (chi 2 = 3.474; p greater than 0.06). Prophylactic antibiotics were administered after 14.0% of the bite wounds, and 3.2% of the lacerations. Infection supervened after prophylactic antibiotics in 29.5% of the bites and 34.6% of the lacerations. No patient with a bite wound required debridement, initial or subsequent surgical intervention other than wound closure, admission to hospital, or intravenous antibiotics. There is no recorded instance of a bite wound complication other than immediate loss of tissue. These data substantiate a higher incidence of infection in human bite wounds, but they are scant support for admonition that such wounds are indication for routine antimicrobial prophylaxis or aggressive surgical intervention.

Anti-Bacterial Agents↗
PubMed1982

Effectiveness of penicillin irrigation in control of infection in sutured lacerations.

We studied the incidence of infection in lacerations in a controlled, double-blind, Armitage sequential clinical trial. After standard prescribed preparation of the wound area, and immediately before suture, each laceration was flooded with the 10 ml content of a numbered, amber glass vial. Half of the vials contained a solution of 0.9% NaCl; half contained a 5% solution of sodium benzyl penicillin. No other factors were controlled. A single observer made the determinations of presence or absence of infection, purulent or nonpurulent, early and late after suture. After study of 260 lacerations the study indicated a clear superiority of penicillin over saline in lowering the incidence of infection with a statistical significance of p less than 0.00005. In a sample of this size the 95% confidence limits of the magnitude of the superiority of penicillin cover a wide range, but it appears that two out of three or three out of four infections can be averted merely by flooding the wound with penicillin immediately before suture.

Clinical Trials as Topic↗
PubMed1982

Educating primary physicians in emergency surgical procedures.

While federal agencies explore ways to encourage physicians to enter primary care practice in underserved areas, they largely avoid the question of how well current training programs prepare physicians for the role. No systematic study has been made of skills in emergency procedures that may be needed in areas where a surgeon is not readily available. A survey of the literature and of our own primary care residents gives cause of concern. Only a third of the residents were confident of their ability to perform a set of procedures essential for stabilizing injured patients. A greater reliance on training in ambulatory clinics, as recommended by the Graduate Medical Education National Advisory Committee (GMENAC), may further decrease opportunities for learning essential technics.

Emergency Medical Services↗
PubMed1979

Modification by dipyrone (noramidopyrine methanesulphonate) of stone-induced ureteric hyperperistalsis in the dog.

Implantation of a stone in the ureter of the dog by ureterotomy results in focal hyperperistalsis which is accentuated by administration of norepinephrine, and reduced by administration of phenoxybenzamine or isoproterenol. Administration of dipyrone reduces the hyperperistalsis, but this action does not appear to be that of either a beta-agonist of an alpha-antagonist.

Aminopyrine↗