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Biomedical subjects

D Leys

Publications and source records attributed to D Leys.

At least 235 records · Page 13Linked to original sources
PubMed1986

[Benign choroid plexus papilloma. 2 local recurrences and intraventricular seeding].

The authors report a case of choroid plexus papilloma developped in the fourth ventricle. After complete surgical resection, two local recurrences of the tumor occurred, and required new surgical procedures. Eight years after the first operation, a papilloma of the right lateral ventricle was resected. The histological examination showed benign choroid plexus papilloma after each operation. Recurrence and seeding of benign choroid plexus papillomas are infrequent in the literature. For this reason, a long-term follow-up, by clinical examination and CT scan, is necessary for those patients.

Adult↗
PubMed1986

[Myocardiopathy disclosing a centronuclear myopathy in an adult].

The authors report the case of a primary myocardiopathy of the young adult, related in fact to a rare muscular congenital disease: centro-nuclear myopathy. The case is different from the classic picture in that it is revealed late, by its cardiac manifestations which dominate the clinical picture and lead to an irreducible cardiac insufficiency requiring a heart transplant. Only a muscular biopsy with histological and histo chemical study permits to make the diagnosis, while the lesions of the myocardium are non-specific.

Adult↗
PubMed1985

[Syringoperitoneal shunting].

In the technique of syringoperitoneal shunting described, a small diameter silicone catheter with lateral openings is introduced through the spinal cord into the lower part of the syringomyelic cavity, then connected to a standard peritoneal shunt tube. Six patients were operated upon using this technique. No major post-operative complication was observed; one patient stabilized and 5 rapidly and distinctly improved. The best results were obtained in patients with sensory loss or arthropathy. It seems rational to apply this technique to active syringomyelia. Permanent shunting maintains low pressure in the cavity and attenuates the effects of sudden, physiological rises in CSF pressure, thus preventing progressive dissection of the nervous tissue.

Catheterization↗
PubMed1985

Decreased morbidity from acute bacterial spinal epidural abscesses using computed tomography and nonsurgical treatment in selected patients.

We describe 5 patients with spinal epidural abscesses in whom computed tomographic scanning confirmed diagnosis without the use of myelography. One patient required urgent surgery because of rapidly deteriorating neurological status, but the other 4 were treated nonsurgically. The medical treatment of these patients and 9 others described in the literature consisted of antibiotics administered parenterally for a minimum of 8 weeks, followed by oral antibiotic therapy. Early diagnosis with computed tomographic scanning and a benign neurological state at the onset of treatment were associated with good results.

Abscess↗
PubMed1985

Spinal intradural arachnoid cysts.

Based on the study of 8 cases of spinal intradural arachnoid cysts, the authors underline that the diagnosis is sometimes difficult because of the limitations of the paraclinical examination. They discuss aetiopathological problems.

Adolescent↗
PubMed1985

Cervical neurological complications of rheumatoid arthritis. Surgical treatment techniques and indications.

A critical study of 11 cases with neurological complications resulting from damage to the cervical spine during rheumatoid arthritis prompts the authors to reconsider their therapeutic strategy. After recalling the various neurological complications and their mechanisms, they propose an extension of the range of indications for surgical treatment. The limits of this extension are defined according to neurological and radiological criteria and the risks inherent in each method.

Adult↗
PubMed1985

Melanotic meningioma. Report of a case and review of the literature.

Melanotic tumours of the central nervous system constitute a group of expanding lesions whose prognosis is variable, depending upon their histopathological nature. The report of this case of melanotic meningioma finds its interest in the exceptional nature of this type of tumour and in the difficulty of ascertaining whether it is benign or malignant.

Adult↗
PubMed1985

[Acute pseudobulbar syndrome. Bilateral infarction of the junction of the internal capsule with the corona radiata].

A 33 year-old hypertensive woman presented with a pure, acute, pseudobulbar palsy, two years after a right transient facio-brachial hemiplegia. C.T. scan showed two areas of low density projecting over the junction of the internal capsule with the corona radiata, at the external border of the lateral ventricles. They involved the territories of both posterolateral choroidal arteries, at the junction with those of the external lenticulostriatal arteries. Clinical data, clinico-pathological correlations in pseudobulbar palsies, and new concepts about the corticobulbar tract anatomy are discussed with evidence from this case.

Acute Disease↗
PubMed1985

[Hydro-syringomyelic cavities. Contributions of x-ray computed tomography and nuclear magnetic resonance. Value of syringoperitoneal shunt].

Twenty one patients with a spinal cord cavity are reported: 14 presented syringomyelia, 3 had a syringomyelic syndrome of another etiology, 4 had clinical symptoms different from those usually observed with such cavities. All patients had a plain C.T. and 20 had a C.T. of cervical and thoracic spinal cord 6 hours after cervical myelography with metrizamide or iopamiron. Morphologic and dynamic features given by this examination are reported. They allowed a discussion about the pathogenesis of the cavity: some cases were consistent with Gardner's theory, but the majority were consistent with Aboulker's. Nine patients had an examination by magnetic resonance imaging which gave the morphologic features necessary for the treatment: spinal cord cavity, Chiari malformation, hydrocephalus. Eleven patients were treated by a syringoperitoneal shunt: in spite of the short follow-up, the results seem favourable, especially for sensitivity and trophic troubles. Surgery should be based upon aggravating course and hydrocephalus. The results of syringoperitoneal shunting allow new considerations about pathogenesis.

Adult↗
PubMed1985

[Acute choreic syndrome and psychotic state induced by an amphetaminic drug].

A twenty-nine year-old woman, with oral contraceptive medication over 10 years, was admitted with chorea and acute psychosis. Fourty-eight hours earlier she had initiated therapy with amphetamine. The mechanisms of these acute manifestations are discussed: oral contraceptives increase striatal post-synaptic dopaminergic sensitivity, while amphetamines facilitate the dopamine release in striatum.

Acute Disease↗
PubMed1984

[Cerebral abscesses disclosing pulmonary angioma. Rendu-Osler disease].

A 50-year old male patient presented with two successive cerebral abscesses over a 9-month period. Rendu-Osler-Weber disease was diagnosed on the basis of recurrent epistaxis and telangiectasis of the mucosae and skin. In addition, many members of the patient's family had a history of epistaxis and one had a cerebral angioma of unusual location. Our patient's chest was normal on physical and radiological examination, but pulmonary angiography disclosed a small angioma. Removal of the angioma prevented further cerebral infections. The prevalence of pulmonary arterio-venous fistulae in Rendu-Osler-Weber disease and their clinical manifestations (especially in the central nervous system) are reviewed, together with the value of family studies and the therapeutic approach.

Brain Abscess↗
PubMed1984

[Acute spinal epidural infections due to common pathogens. 23 cases].

Twenty-three cases of acute spinal epidural infection due to common pathogens were retrospectively studied. Pain is not always present initially and usually appears 15 to 32 days after the primary infection, which is only found in one-half of the cases. When established, the condition is characterized by spinal rigidity, signs of infection, and compression of the cord or cauda equina. The diagnosis is confirmed by surgery, radiology (myelographic blockade, spondylodiscitis) or the finding of pus in the epidural space at lumbar puncture. A frequently delayed diagnosis explains the poor prognosis of these infections. Treatment should always include an antibiotic active against staphylococci, which are by far the most common pathogens. The indications for surgery are discussed in the light of published data compared to the authors' own experience.

Acute Disease↗