Search PubMedSearch

Biomedical subjects

D Laub

Publications and source records attributed to D Laub.

16 recordsLinked to original sources

Fluorescein angiography of the bladder: technique and relevance to bladder cancer and interstitial cystitis patients.

PURPOSE: Fluorescein angiography has been used in the study of bleeding vessels, neovascularity, tumors and ischemic tissues in a variety of disorders. This pilot study was designed to evaluate the feasibility, safety and relevance of this interesting technology for the evaluation of bladder wall vessels in patients with interstitial cystitis and bladder cancer. MATERIALS AND METHODS: Five patients with National Institutes of Health defined interstitial cystitis symptoms and 10 with bladder cancer were studied during cytoscopy while they were under general anesthesia. A yellow-green barrier filter (520 nm.) was placed over the cystoscope eyepiece and a blue exciter filter (465 nm.) was attached to the light source. Patients received a 5 ml. bolus of 10% fluorescein intravenously. RESULTS: After hydrodistension, glomerulations in interstitial cystitis patients were more prominent with fluorescein angiography and occurred in the venule phase. Areas of papillary transitional cell tumor and carcinoma in situ developed a brilliant yellow-green fluorescence. Adjacent normal urothelium was nonfluorescent and provided a contrasting dark background facilitating the detection of all lesions. No allergic reaction or other adverse effect related to the fluorescein injection was observed. CONCLUSIONS: These unique observations in a limited number of patients suggest that fluorescein angiography of the bladder is a safe and simple procedure. This preliminary report underscores the relevance of fluorescein angiography in the detection of bladder tumor and offers a new approach to the evaluation of bladder wall vessels in interstitial cystitis patients.

Arterioles

Narrative constructions of historical realities in testimony with Bosnian survivors of "ethnic cleansing".

Mental health care for traumatized refugees includes practices common to mainstream mental health care but also modifications and innovations in technique and approach. One such innovation, the testimony method, was first described by a group of Chilean psychiatrists working with Chilean survivors of torture from political repression (Cienfuego and Monelli 1983). The testimony method has been used as a time-limited psychotherapeutic intervention, often within the context of an extended, supportive psychotherapy. This method consists of asking individuals to tell in detail the story of their experiences of victimization from state-sponsored violence and recording their narrative accounts verbatim. Agger and Jensen's account of this method depicts testimony as a universal practice, appearing in multiple cultures and at different points in history (Agger and Jensen 1990). They also note that testimony simultaneously functions in both the private and public domains; and as confession embodying the person's spiritual, ethical, aesthetic, and philosophical values, and as evidence documenting the occurrence of evil events to the world.

Adult

Psychiatric consequences of "ethnic cleansing": clinical assessments and trauma testimonies of newly resettled Bosnian refugees.

OBJECTIVE: The authors describe the psychiatric assessments and trauma testimonies of 20 Bosnian refugees of "ethnic cleansing" who have recently resettled in the United States. METHOD: Refugees referred from agencies managing refugee resettlement underwent systematic, trauma-focused, clinical interviews that included standardized assessment scales. RESULTS: The traumatic experiences of ethnic cleansing in these Bosnian refugees were genocidal in nature. The number of types of traumatic experiences correlated positively with age. Posttraumatic stress disorder (PTSD) was diagnosed in 65% of the refugees, and depressive disorders in 35%. PTSD severity scores were correlated with the number of types of traumatic events experienced. CONCLUSIONS: Ethnic cleansing has caused high rates of PTSD and depression, as well as other forms of psychological morbidity, in this group of resettled Bosnian refugees. The longitudinal sequelae of ethnic cleansing as a form of massive psychic trauma remain to be studied.

Adolescent

[The second Holocaust: life is threatening].

According to the author's observations, the "second holocaust" is a phenomenon encountered both in the first and the second generation. This dramatic concept seeks to convey the fact that the devastations of the actual holocaust are re-enacted and unconsciously repeated by the survivors and their children in terms not only of the content of the trauma but also of its style. Referring to a number of potted case histories, the authors describe how inevitable and absolute the shadow of destruction is felt to be by the victims and how the contrive to survive under this shadow. From a therapeutic viewpoint it appears helpful to encounter the onset and the effects of this "second holocaust" by activating the life side of the life-death dichotomy as a counter against the compulsive urge for repetition. Life, through felt itself to be permanently at risk, must be made to function as the motor for the negation of death.

Adult

[The search for historical truth: psychotherapeutic work with Bosnian refugees].

The trauma haunting refugees from ex-Yugoslavia is inextricably bound up with complex processes of historical change. In order to be able to understand and treat their severe psychic problems, psychotherapists have to go in search of the historical truth, which is frequently masked by myths and obsolete notions. Only when a psychotherapist who has received the relevant interdisciplinary schooling acknowledges the existence of completely new historical experiences can s/he provide effective support for Bosnian Muslims fleeing "ethnic cleansing" and attempting to achieve self-healing, learning and growth after such an extreme form of collective and individual destruction. In this way the psychotherapist becomes an initiated listener and a unique witness of a form of historical truth that for the traumatized patients themselves is at first entirely or largely beyond recall and comprehension.

Bosnia and Herzegovina

The challenge of kidney transplant nephrectomy.

During a 5-year-period 92 kidney transplant nephrectomies were performed and 87% of these kidneys were removed by a subcapsular technique. Surgical complications occurred in 4% of the cases. Renal allograft nephrectomy is a more complex and riskier operation than simple native nephrectomy.

Adult

Knowing and not knowing massive psychic trauma: forms of traumatic memory.

It is in the nature of trauma to elude knowledge, both because of deficit and defence. Massive trauma cannot be grasped because there are neither words nor categories of thought adequate to its representation; knowledge of trauma is also fiercely defended against, as it poses a momentous threat to psychic integrity. Yet knowing nevertheless occurs on some level, often in restricted or defensive forms. This paper sets forth various forms of knowing and not knowing massive historical trauma as manifested in clinical symptomatology, transference phenomena, life themes and witnessing narratives. Metaphor is also mentioned as yet another form of knowing and addressing trauma, available primarily to those who have not been directly affected as victims nor as family members of victims. The different forms imply a continuum of progressively more integrated and subjectively owned levels of knowing, directly related to the actual and psychological distance from the traumatic event. Illustrations drawn from clinical and testimonial settings are given for each level of knowing described, and implications for therapeutic strategy are discussed.

Adult

Custom-fabricated silicone implants for contour restoration.

A 15-year review is made of contour restoration by custom silicone inlay technique. Eighty-three patients have undergone surgery since 1962. The indications, preparation of moulage and implant, surgical technique, and care of complications are described. The custom silicone technque has proved successful, precise, and relatively free of complications. Tolerance of uncomplicated implants has been permanent.

Adolescent