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Biomedical subjects

D Lask

Publications and source records attributed to D Lask.

25 records · Page 2Linked to original sources

Evoked response studies in detrusor hyperreflexia due to infravesical obstruction in neurological patients.

Urodynamic evaluation was performed on 80 patients with urological disorders identified as benign prostatic hypertrophy whose main complaints ranged from irritation to urine loss owing to urgency. Detrusor hyperreflexia was detected in 40 patients, of whom 24 were operated on either by the transurethral or the retropubic approach. At repeat urodynamic evaluation about 1 year postoperatively function had returned to normal in 14 patients and the hyperreflexia persisted in 10. The preoperative evoked response in these latter 10 patients was less than 60 msec. It is possible that apart from the diagnosis of detrusor hyperreflexia by cystometric examination in patients with benign prostatic hypertrophy an abbreviated evoked response could indicate deterioration in neural function with or without an accompanying neurological disease. If this is the cause of detrusor hyperreflexia then prostatectomy will not ameliorate the condition but can only subject the patient to the risk of urine loss.

Aged↗

Concomitance of urogenital with lymphoid and intestinal malignancies: more than a coincidence.

Concomitance of different primary malignant neoplasms in the same individual has been observed and explained by several possible mechanisms. For urogenital malignancies in concomitance with lymphoid or with intestinal malignancies some data indicate that common etiologic factor(s) with pleiotropic effects may be involved. Concomitance of these particular different primary malignant neoplasms must therefore be kept in mind in the evaluation of patients' conditions.

Aged↗

Megacalycosis.

Megacalycosis is a primary disease of the renal calyx which is diagnosed usually because of its complications, such as calculi or infections in the urinary tract. In the absence of complications, the disease is discovered accidentally in the course of urologic examination undertaken for a different reason. The present article reports 4 cases of megacalycosis: one with histologic confirmation in addition to radiologic diagnostic criteria and 3 with diagnosis based on radiologic findings alone. Alertness to the possible existence of megacalycosis in patients suffering from infections and calculi in the urinary tract contributes to and facilitates choice of appropriate treatment.

Dilatation, Pathologic↗

Congenital polyp of the prostatic urethra.

Congenital polyp of the urethra is a rare cause of urine retention in male patients. Diagnosis is made via cystourethrography and is confirmed by transurethral biopsy. Although the recent literature contains several reports on the use of transurethral resection the preferred surgical procedure yielding the best results is transvesical excision of the polyp.

Child, Preschool↗

[Diagnosis and surgical treatment of female urinary stress incontinence].

A total of 100 female patients with putative urinary stress incontinence (USI) were surveyed by us. Of these, 27 patients with genuine USI underwent urologic, uroradiologic and urodynamic evaluations before and after their corrective surgery by the technique of Burch. The results of the surgery were assessed clinically and subjectively and compared to the data obtained from postoperative urodynamic analysis. The operation affected significantly the urethral closure pressure and the posterior angle between the urethra and the base of the bladder, bringing about marked clinical improvement in most of the patients. Thus 89.5% of operated patients were cured, while elevated urethral closure pressure was proven in the majority of cases and radiologic examinations showed correction of the anatomic fault in 82% of the women undergoing surgery. Correct diagnosis is the most important antecedent of treatment in female urinary stress incontinence. Any surgical approach which affixes the neck of the bladder and the posterior part of the urethra to a stable support is sufficient to effect correction of the condition, provided the incontinence stems from a weakness in the closure mechanism of the urethra and not from some other cause.

Electromyography↗

Multiple myeloma associated with Kaposi sarcoma.

A patient with multiple myeloma (MM) who developed Kaposi sarcoma (KS) is described. The KS appeared 18 months after the diagnosis of MM and 1 month after the treatment was changed from cyclophosphamide to melphalan. The treatment with melphalan was discontinued and the spread of the KS was arrested by irradiation and bleomycin. One month after the melphalan was restarted, the KS advanced. The patient died 28 months after the diagnosis of MM and 10 months after KS had developed. The association of KS and MM is discussed and the previously reported cases are reviewed. A possible connection between the treatment with melphalan and the development of KS is proposed.

Bleomycin↗