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Biomedical subjects

D Larochelle

Publications and source records attributed to D Larochelle.

13 recordsLinked to original sources
PubMed1986

Capnocytophaga ochracea and group F beta-hemolytic streptococcus suppurative thyroiditis.

The route of infection in acute suppurative thyroiditis is unknown in most cases; when demonstrated, pyriform sinus fistula appears to be the most frequent one. We report the clinical and laboratory findings of a child in whom culture of the thyroid pus yielded two bacteria which are part of the normal oropharyngeal flora: capnocytophaga ochracea and group F Beta-hemolytic streptococcus. The preliminary results of the culture, which showed a mixed flora, prompted us to search and to find a pyriform sinus fistula. Apart from the onset in infancy, the left lobe involvement and the frequent recurrence, the recovery from the thyroid pus of bacteria from normal oropharyngeal flora should be included in the characteristic features of thyroiditis resulting from an infection through the pyriform sinus fistula.

Adolescent↗
PubMed1982

Phase I study of 13-cis-retinoic acid toxicity.

A phase I study of 13-cis-retinoic acid was done in 16 patients with head and neck malignancies using a modified Fibonacci search scheme, with individual doses ranging from 20 to 120 mg/m2. Drug doses greater than 60 mg/m2 induced intense headaches, urethritis, desquamative dermatitis, vertigo, and ataxia. The severity of these side effects precludes the use of 13-cis-retinoic acid as a potential chemopreventive agent at doses greater than 60 mg/m2.

Adult↗
PubMed1979

Homografts of the middle ear. Privileged tissue or privileged site.

To explain the survival and behavior of homografts, we have tried, by means of discussion and use of biological models, to resolve a problem with three unknowns, ie, the tympanic membrane, the ossicle, and the middle ear, with the notions of privileged tissue and privileged site. The tympanic membrane survives because of the relative stability of its fibers and the absence of mechanical trauma. Later, the membrane is sheathed by fibrous tissue. The ossicle is not only tolerated by the host but is also invaded and ossified.

Ear Ossicles↗
PubMed1979

Ectopic thyroid tissue--a review of the literature.

With only two cases in 20 years in their service and considering the low incidence of ectopic thyroid gland, the authors present a review of the literature with emphasis on clinical and pathological description and modern medical or surgical management of this entity known as ectopic thyroid gland.

Adolescent↗
PubMed1978

Drawing: a universal language.

The authors insist on the importance of drawing through the centuries to recall ways of life. They try to pinpoint the utility of drawing in this day and age, making perioperative drawing reports concise and clear with a few lines. Basic sketches are explained and illustrated.

Communication↗
PubMed1977

Thrombosis of the lateral sinus.

Four cases of lateral sinus thrombosis have been treated at Notre-Dame Hospital, Montreal, since 1960. A review of the literature of this pathology is reported, and two cases treated in the past three months are presented.

Adult↗
PubMedDate not supplied

Sudden death in turkeys with perirenal hemorrhage: pathological observations and possible pathogenesis of the disease.

A pathological study was conducted on 32 turkeys that died of sudden death with perirenal hemorrhage syndrome. Turkeys were selected from routine necropsy cases in a diagnostic laboratory. A higher incidence was observed in heavy tom turkeys. In addition to the characteristic gross lesions of perirenal hemorrhage, splenomegaly, and pulmonary congestion, turkeys in most cases had a hypertrophic cardiopathy. Microscopic lesions included moderate-to-marked acute passive congestion of all tissues examined (32/32), severe perirenal hemorrhage (32/32), and splenic lymphoid depletion (25/32). Changes in the thyroid follicular epithelium of most birds suggested an increased glandular activity. No lesions suggestive of arterial hypertension were observed. Adenoviral infection was detected in only four of 32 birds. Bacteriological cultures revealed no significant pathogen. Results suggest that sudden death in turkeys with perirenal hemorrhage is caused by an acute congestive heart failure consecutive to a hypertrophic cardiopathy. The perirenal hemorrhage would be a consequence of a severe passive congestion in kidneys.

Animals↗