Search PubMed⌕ Search

Biomedical subjects

D Laky

Publications and source records attributed to D Laky.

At least 19 recordsLinked to original sources
PubMed1993

An uncommon gastric tumour: leiomyoma associated with osteochondroma.

The case of a 65-year-old man having a large gastric tumor for about 6 years, revealed echographically, is reported. A well delimited consistent white-grey tumor of 8 x 6 x 2.5 cm occurring in the anterior wall of the stomach that extended to the peritoneal cavity was surgically found. Histologically it showed leiomyomatous zones with fascicular spindle cells and sometimes with perinuclear vacuolizations, which were actin-reaction positive but S-100 protein negative. These zones alternated with large compact benign osteochondromatous zone. The uncertain origin of this uncommon tumor was discussed. We have not found any references to such gastric tumors.

Aged↗
PubMed1986

Gastric liposarcoma. A case report.

Gastric localization of a liposarcoma is exceptional. A 67 year old patient with repeated hematemesis was found to have an ulcer on the dorsal wall of the antrum on radiology. Surgery revealed an ulcerated tumour, 5 X 2 X 1.5 cm, involving the tunica muscularis up to the serosa. Histologic examination showed a liposarcoma with intricate myxomatous zones, round cells, pleomorphous clearly differentiated lipoblastic aspects, and haemorrhagic areas.

Aged↗
PubMed1983

The protective action of prostaglandins E2 and F2 alpha on antibody induced myocardial lesions: morphological studies.

Optic and electron microscopical investigations as well as histochemical investigations were performed in rats which have intraperitoneally received an anti-rat serum together with either PGE2 or PGF2 alpha, in order to study the effect of these prostaglandins on antibody-induced myocardial lesions. PGE2 and, especially, PGF2 alpha were found to considerably prevent the myocardium against these lesions (mononuclear cell infiltration, interstitial and intracellular hyperhydration, disintegration of myofibrils, vacuolization of sarcoplasmic reticulum, mitochondrial swelling and degradation, lysosomal activation and disruption of myocardial sarcolemmas and blood capillary membranes). Their protective actions were revealed in animals killed 24 h and 6 days after the administration of anti-rat immunoglobulins.

Animals↗
PubMed1982

Experimental studies in transient myocardial ischaemia.

The biology of the myocardium was studied under experimental conditions similar to angina pectoris. In some dogs the myocardium was adapted to ischaemia by progressive coronary occlusion of 1-5 min followed by restoration of circulation during 5 min. In other dogs adaption was followed by 20 to 35 min ischaemia. The animals were sacrificed immediately or after 2-10 days. Transient ischaemia produced less severe alterations then abrupt coronary obstruction. Adaptation followed by 20 and 35 min ischaemia induced foci that undergo cytolysis and scarring of maximum intensity on the 8th day. Activity of enzymes in the mitochondrial suspension, especially of cytochromoxidase, decreases and lysosomal hydrolases increase with focal necroses.

Angina Pectoris↗
PubMed1976

Immunomorphological lymph node processes in some cirrhogenic liver diseases.

Dynamics of the lymph node modifications as well as hepatic and immunoserological in various cirrhogenic hepatopathies have been studied on human and experimental material. Lymph nodes showed early and progressively immunomorphological reactions with maximum intensity in evolutive stages of certain cirrhoses. Such reactions as well as in other areas of reticulo-endothelial system are decreasing during the immunosuppressive treatment and in advanced stages of cirrhosis. The lymph nodes participation in the pathogenic mechanism of some cirrhogenic hepatopathies has been very little studied, whereas that of the liver and of the spleen has been more approached. Our previous investigations (1) have disclosed the existence of some chronic lymphadenites as well as reactional reticuloses on necroptic material from young cirrhotics. Equally, during some preliminary experimental studies (7) We remarked intense lymph node reactions even in incipient phases of cirrhoses, which fact stirred us up to examine them thoroughly.

Adult↗