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Biomedical subjects

D L Weiss

Publications and source records attributed to D L Weiss.

At least 37 records · Page 2Linked to original sources

Carcinoma in situ of the gallbladder: A dilemma.

The prognosis for advanced carcinoma of the gallbladder is grave, but a reappraisal of the histologic and gross presentation of the disease may uncover a group of patients with significantly better prognosis. During any cholecystedtomy, the gallbladder should be opened by the surgeon and frozen sections should be obtained for suspicious lesions. Carcinoma in situ appears to be well treated by cholecstectomy alone. Microinvasive carcinomas of the gallbladder require wider surgical excision

Adult↗

Inflammatory potential of foreign particulates in parenteral drugs.

Particulate and bacterial contamination of IV fluids and drugs have been implicated in venous thrombosis, infusion phlebitis, suppurative thrombophlebitis, pyrogenic reactions, and systemic sepsis. In a study of the inflammatory potential of the filterable residue of sodium cephalothin, we have found a tissue-specific reaction with venous endothelium but not with cutaneous or subcutaneous tissues. In a controlled animal model, removal of particulates from an infusion by use of a 0.45 micron in-line membrane filter reduces the incidence and severity of infusion phlebitis.

Animals↗

Acute bacterial arthritis.

Analysis of 29 consecutive cases of acute bacterial arthritis requiring hospitalization reveals the importance of local and systemic immunologic states or conditions which reduce the efficacy of immune responses in the establishment of joint infections. The complications of trauma and surgery are considered as interfering with the normal local immune response.

Acute Disease↗